1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. 1-Methylhistamine

1-Methylhistamine is a histamine (Him) metabolite.

For research use only. We do not sell to patients.

1-Methylhistamine Chemical Structure

1-Methylhistamine Chemical Structure

CAS No. : 501-75-7

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Based on 1 publication(s) in Google Scholar

Other Forms of 1-Methylhistamine:

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Description

1-Methylhistamine is a histamine (Him) metabolite.

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

1-Methylhistamine is a histamine metabolite. It is a product of histamine 1-methyltransferase in the pathway of histidine metabolism.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

125.17

Formula

C6H11N3

CAS No.
Appearance

Liquid (Density: 1.11±0.1 g/cm3)

Color

Colorless to light yellow

SMILES

NCCC1=CN(C)C=N1

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (798.91 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 7.9891 mL 39.9457 mL 79.8913 mL
5 mM 1.5978 mL 7.9891 mL 15.9783 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 7.9891 mL 39.9457 mL 79.8913 mL 199.7284 mL
5 mM 1.5978 mL 7.9891 mL 15.9783 mL 39.9457 mL
10 mM 0.7989 mL 3.9946 mL 7.9891 mL 19.9728 mL
15 mM 0.5326 mL 2.6630 mL 5.3261 mL 13.3152 mL
20 mM 0.3995 mL 1.9973 mL 3.9946 mL 9.9864 mL
25 mM 0.3196 mL 1.5978 mL 3.1957 mL 7.9891 mL
30 mM 0.2663 mL 1.3315 mL 2.6630 mL 6.6576 mL
40 mM 0.1997 mL 0.9986 mL 1.9973 mL 4.9932 mL
50 mM 0.1598 mL 0.7989 mL 1.5978 mL 3.9946 mL
60 mM 0.1332 mL 0.6658 mL 1.3315 mL 3.3288 mL
80 mM 0.0999 mL 0.4993 mL 0.9986 mL 2.4966 mL
100 mM 0.0799 mL 0.3995 mL 0.7989 mL 1.9973 mL
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
1-Methylhistamine
Cat. No.:
HY-W062542
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