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Microbial Metabolite Library

Cat. No.: HY-L084

Nature has been a source of medicinal products for millennia, with many useful active substances developed from plant sources. In the 20th century, the discovery of the penicillin was the starting point for drug discovery from microbial sources. Microorganisms， which have been considered to be a rich source of unique bioactive compounds, play an important role in the development of the chemistry of natural products and medical therapy. Microbial metabolites have proved to be affective antimicrobial agents, anti-tumor agents, enzyme inhibitors, anti-inflammatory agents, etc. Today, many microbial-originated antibiotics are available in the mark, and a large number of bioactive metabolites are used in medicine.

MCE provides a unique collection of 1,121 microbial metabolites, which is an important source of lead compounds and can be used for drug discovery.

For pre-dissolved solutions, 10 mM for compounds with the solubility not lower than 10 mM, 2 mM for compounds with solubility between 2 mM and 10 mM, and 3 mg/mL for compounds with unconfirmed molecular weight and solubility not lower than 3 mg/mL.

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
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Description & Advantages

•   A unique collection of 1,121 microbial metabolites for high throughput screening (HTS) and high content screening (HCS).

•   All compounds derived from microbes with better bioavailability.

•   A useful tool for microbial metabolites-related drug discovery.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some compounds have been approved by FDA.

•   Structurally diverse, bioactive, and cell permeable.

•   More detailed compound information with structure, IC50, and brief introduction.

•   High purity and quality validated by NMR and LC/MS.

•   All compounds are in stock and continuously updated.

Product Details

Formulation:

A collection of 1,121 microbial metabolite related compounds supplied as pre-dissolved Solutions or Solid
Solution: 1,073 compounds supplied in 10 mM solution, 32 compounds supplied in 2 mM solution, 16 compounds supplied in 3 mg/mL solution.

Layout:

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container:

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage:

-80°C

Shipping:

Blue ice or dry ice

Composition

COX (14)

HSV (13)

HIV (12)

iGluR (11)

MMP (8)

PI3K (8)

PPAR (7)

PKC (6)

Akt (5)

STAT (5)

AMPK (4)

EGFR (4)

ERK (4)

JNK (4)

mTOR (4)

PKA (4)

FKBP (3)

PARP (3)

Wnt (3)

BCL6 (2)

CDK (2)

CXCR (2)

FGFR (2)

FXR (2)

HBV (2)

HCV (2)

HDAC (2)

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Compound Customization
  •  Specific Compounds
  •  Quantities
  •  Plate Map
  •  Concentration
  •  Form (Solid or Solution)
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    Product Name:
    Microbial Metabolite Library
    Cat. No.:
    HY-L084
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    • 96-well Plate with Peelable Foil Seal
    • 384-well Microplate with Peelable Foil Seal
    • 96-well Storage Tubes with Rack
    • 96-well Plate with Peelable Foil Seal
    • 384-well Microplate with Peelable Foil Seal
    • 96-well Storage Tubes with Rack

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