2. PI3K/Akt/mTOR Apoptosis
  3. Akt Apoptosis
  4. 2-Chlorophenoxazine

2-Chlorophenoxazine is a Akt inhibitor with an IC50 value of 2-5 μM for in vitro. 2-Chlorophenoxazine can induce apoptosis. 2-Chlorophenoxazine can be used for cancer diseases research.

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2-Chlorophenoxazine Chemical Structure

2-Chlorophenoxazine Chemical Structure

CAS No. : 56821-03-5

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2-Chlorophenoxazine Related Antibodies

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Description

2-Chlorophenoxazine is a Akt inhibitor with an IC50 value of 2-5 μM for in vitro. 2-Chlorophenoxazine can induce apoptosis. 2-Chlorophenoxazine can be used for cancer diseases research[1].

Cellular Effect
Cell Line Type Value Description References
K562 IC50
> 30 μM
Compound: 28
Antiproliferative activity against human K562 cells after 48 hrs by hemocytometric analysis
Antiproliferative activity against human K562 cells after 48 hrs by hemocytometric analysis
[PMID: 21563750]
Molecular Weight

217.65

Formula

C12H8ClNO
CAS No.
SMILES

ClC(C=C1N2)=CC=C1OC3=C2C=CC=C3
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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2-Chlorophenoxazine Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2-Chlorophenoxazine56821-03-5AktApoptosisPKBProtein kinase BchlorophenoxazineapoptosisInhibitorinhibitorinhibit

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