2'-Deoxycytidine-¹³C₉,¹⁵N₃  (Synonyms: Deoxycytidine-¹³C₉,¹⁵N₃; Cytosine deoxyriboside-¹³C₉,¹⁵N₃; Deoxyribose cytidine-¹³C₉,¹⁵N₃)

2'-Deoxycytidine-¹³C₉,¹⁵N₃ (Deoxycytidine-¹³C₉,¹⁵N₃; Cytosine deoxyriboside-¹³C₉,¹⁵N₃; Deoxyribose cytidine-¹³C₉,¹⁵N₃) is ¹³C and ¹⁵N-labeled 2'-Deoxycytidine (HY-D0184). 2'-Deoxycytidine, a deoxyribonucleoside, could inhibit biological effects of Bromodeoxyuridine (Brdu).

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

239.13

¹³C₉H₁₃¹⁵N₃O₄

1987883-22-6

951-77-9

Liquid

Colorless to light yellow

O=[13C]1[15N]([13C@H]2[13CH]([H])[13CH](O)[13C@@H]([13CH2]O)O2)[13CH]=[13CH][13C]([15NH2])=[15N]1

Room temperature in continental US; may vary elsewhere.

Solution, -20°C, 2 years

• [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  [Content Brief]

  [2]. Horn D, et al. Inhibition of biological effects of bromodeoxyuridine by deoxycytidine: correlation with decreased incorporation of bromodeoxyuridine into DNA. Somatic Cell Genet. 1976 Sep;2(5):469-81.  [Content Brief]