2. Antibody-drug Conjugate/ADC Related
  3. ADC Linker
  4. (2-pyridyldithio)-PEG1-hydrazine

(2-pyridyldithio)-PEG1-hydrazine 

Cat. No.: HY-136135 Purity: 99.30%
SDS COA Handling Instructions

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(2-pyridyldithio)-PEG1-hydrazine is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

For research use only. We do not sell to patients.

(2-pyridyldithio)-PEG1-hydrazine Chemical Structure

(2-pyridyldithio)-PEG1-hydrazine Chemical Structure

CAS No. : 111625-28-6

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Based on 1 publication(s) in Google Scholar

(2-pyridyldithio)-PEG1-hydrazine Related Antibodies

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Description

(2-pyridyldithio)-PEG1-hydrazine is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target

Disulfide Cleavable Linker

 

Cleavable Linker

 

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

(2-pyridyldithio)-PEG1-hydrazine Related Antibodies
Molecular Weight

187.28

Formula

C7H9NOS2
CAS No.
Appearance

Solid-Liquid Mixture

Color

Colorless to light yellow

SMILES

OCCSSC1=NC=CC=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Purity & Documentation

Purity: 99.30%

SDS (477 KB)

COA (244 KB) HNMR (128 KB) RP-HPLC (189 KB)

Handling Instructions (2659 KB)
References
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(2-pyridyldithio)-PEG1-hydrazine Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(2-pyridyldithio)-PEG1-hydrazine111625-28-6ADC LinkerAntibody-drug conjugates linkerInhibitorinhibitorinhibit

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