3α-Hydroxymogrol

Cat. No.: HY-N6913 Purity: 99.88%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

3α-Hydroxymogrol is a triterpenoid isolated from Siraitia grosvenorii Swingle, acts as a potent AMPK activator, and enhances AMPK phosphorylation.

For research use only. We do not sell to patients.

3α-Hydroxymogrol Chemical Structure

CAS No. : 1343402-73-2

Size	Price	Stock	Quantity
1 mg	USD 250	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 700	In-stock	Estimated Time of Arrival: December 31
10 mg		Get quote
50 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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NUAK1 NUAK2 AMPK AMPK α1β1γ1 AMPK α2β1γ1 AMPK α1β2γ1 AMPK α2β2γ1

Biological Activity
Purity & Documentation
References
Customer Review

Description

3α-Hydroxymogrol is a triterpenoid isolated from Siraitia grosvenorii Swingle, acts as a potent AMPK activator, and enhances AMPK phosphorylation^[1].

IC₅₀ & Target^[1]

AMPK

Molecular Weight

476.73

Formula

C₃₀H₅₂O₄

CAS No.

1343402-73-2

Appearance

Solid

Color

White to off-white

SMILES

C[C@]12[C@@]3([H])[C@]([C@@]4([H])C(C(C)([C@H](O)CC4)C)=CC3)([C@H](O)C[C@@]1([C@]([C@H](C)CC[C@@H](O)C(C)(O)C)([H])CC2)C)C

Structure Classification

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (209.76 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.0976 mL	10.4881 mL	20.9762 mL
5 mM	0.4195 mL	2.0976 mL	4.1952 mL
10 mM	0.2098 mL	1.0488 mL	2.0976 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.88%

Select Batch:

Data Sheet (271 KB) SDS (252 KB)

COA (252 KB) HNMR (155 KB) CNMR (164 KB) RP-HPLC (159 KB) MS (179 KB)

Handling Instructions (2659 KB)

References

[1]. Chen XB, et al. Potential AMPK activators of cucurbitane triterpenoids from Siraitia grosvenorii Swingle. Bioorg Med Chem. 2011 Oct 1;19(19):5776-81. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.0976 mL	10.4881 mL	20.9762 mL	52.4406 mL
	5 mM	0.4195 mL	2.0976 mL	4.1952 mL	10.4881 mL
	10 mM	0.2098 mL	1.0488 mL	2.0976 mL	5.2441 mL
	15 mM	0.1398 mL	0.6992 mL	1.3984 mL	3.4960 mL
	20 mM	0.1049 mL	0.5244 mL	1.0488 mL	2.6220 mL
	25 mM	0.0839 mL	0.4195 mL	0.8390 mL	2.0976 mL
	30 mM	0.0699 mL	0.3496 mL	0.6992 mL	1.7480 mL
	40 mM	0.0524 mL	0.2622 mL	0.5244 mL	1.3110 mL
	50 mM	0.0420 mL	0.2098 mL	0.4195 mL	1.0488 mL
	60 mM	0.0350 mL	0.1748 mL	0.3496 mL	0.8740 mL
	80 mM	0.0262 mL	0.1311 mL	0.2622 mL	0.6555 mL
	100 mM	0.0210 mL	0.1049 mL	0.2098 mL	0.5244 mL