2. Epigenetics PI3K/Akt/mTOR
  3. AMPK
  4. 3α-Hydroxymogrol

3α-Hydroxymogrol is a triterpenoid isolated from Siraitia grosvenorii Swingle, acts as a potent AMPK activator, and enhances AMPK phosphorylation.

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3α-Hydroxymogrol Chemical Structure

3α-Hydroxymogrol Chemical Structure

CAS No. : 1343402-73-2

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5 mg USD 700 In-stock
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Based on 1 publication(s) in Google Scholar

3α-Hydroxymogrol Related Antibodies

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NUAK1 NUAK2 AMPK AMPK α1β1γ1 AMPK α2β1γ1 AMPK α1β2γ1 AMPK α2β2γ1

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Description

3α-Hydroxymogrol is a triterpenoid isolated from Siraitia grosvenorii Swingle, acts as a potent AMPK activator, and enhances AMPK phosphorylation[1].

IC50 & Target[1]

AMPK

 

Molecular Weight

476.73

Formula

C30H52O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[C@]12[C@@]3([H])[C@]([C@@]4([H])C(C(C)([C@H](O)CC4)C)=CC3)([C@H](O)C[C@@]1([C@]([C@H](C)CC[C@@H](O)C(C)(O)C)([H])CC2)C)C
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (209.76 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0976 mL 10.4881 mL 20.9762 mL
5 mM 0.4195 mL 2.0976 mL 4.1952 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.0976 mL 10.4881 mL 20.9762 mL 52.4406 mL
5 mM 0.4195 mL 2.0976 mL 4.1952 mL 10.4881 mL
10 mM 0.2098 mL 1.0488 mL 2.0976 mL 5.2441 mL
15 mM 0.1398 mL 0.6992 mL 1.3984 mL 3.4960 mL
20 mM 0.1049 mL 0.5244 mL 1.0488 mL 2.6220 mL
25 mM 0.0839 mL 0.4195 mL 0.8390 mL 2.0976 mL
30 mM 0.0699 mL 0.3496 mL 0.6992 mL 1.7480 mL
40 mM 0.0524 mL 0.2622 mL 0.5244 mL 1.3110 mL
50 mM 0.0420 mL 0.2098 mL 0.4195 mL 1.0488 mL
60 mM 0.0350 mL 0.1748 mL 0.3496 mL 0.8740 mL
80 mM 0.0262 mL 0.1311 mL 0.2622 mL 0.6555 mL
100 mM 0.0210 mL 0.1049 mL 0.2098 mL 0.5244 mL
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3α-Hydroxymogrol Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

3α-Hydroxymogrol1343402-73-2AMPKAMP-activated protein kinaseInhibitorinhibitorinhibit

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