AMPK Inhibitors

NUAK1

NUAK2

AMPK

AMPK α1β1γ1

AMPK α2β1γ1

AMPK α1β2γ1

AMPK α2β2γ1

AMPK Inhibitors & Activators

Product Name	NUAK1	NUAK2	AMPK	AMPK α1β1γ1	AMPK α2β1γ1	AMPK α1β2γ1	AMPK α2β2γ1	Purity
Dorsomorphin			AMPK, Ki: 109 nM					99.91%
Metformin			AMPK					99.98%
AICAR			AMPK					99.98%
Dorsomorphin dihydrochloride			AMPK, Ki: 109 nM					99.91%
Metformin hydrochloride			AMPK					99.92%
A-769662			AMPK, EC₅₀: 0.8 μM					99.20%
MK8722			AMPK					99.37%
Bempedoic acid			AMPK					99.97%
[6]-Gingerol			AMPK					99.45%
AICAR phosphate			AMPK					99.98%
Phenformin hydrochloride			AMPK					99.29%
EX229				AMPK α1β1γ1, Kd: 0.06 μM	AMPK α2β1γ1, Kd: 0.06 μM	AMPK α1β2γ1, Kd: 0.51 μM		98.45%
PF-06409577				AMPK α1β1γ1, EC₅₀: 7 nM				99.44%
WZ4003	NUAK1, IC₅₀: 20 nM	NUAK2, IC₅₀: 100 nM						98.03%
HTH-01-015	NUAK1, IC₅₀: 100 nM							98.81%
Palmitelaidic Acid			AMPK					≥99.0%
Danthron			AMPK					99.19%
MOTS-c(human) acetate			AMPK					98.97%
MRT199665	NUAK1, IC₅₀: 3 nM	NUAK2, IC₅₀: 120 nM						99.74%
Narazaciclib	ARK5, IC₅₀: 5 nM							99.12%
ASP4132			AMPK, EC₅₀: 18 nM					99.32%
PF-739				AMPK α1β1γ1, EC₅₀: 8.99 nM	AMPK α2β1γ1, EC₅₀: 5.23 nM	AMPK α1β2γ1, EC₅₀: 126 nM	AMPK α2β2γ1, EC₅₀: 42.2 nM	98.05%
Metformin-d₆ hydrochloride			AMPK					98.79%
Ginkgolide C			AMPK					≥98.0%
RSVA405			AMPK, EC₅₀: 1 μM (in cell-based assays)					99.72%
MK-3903			AMPK, EC₅₀: 8 nM					98.03%
ZLN024 hydrochloride				AMPK α1β1γ1, EC₅₀: 0.42 μM	AMPK α2β1γ1, EC₅₀: 0.95 μM		AMPK α2β2γ1, EC₅₀: 0.13 μM	98.47%
8-Chloroadenosine			AMPK					99.97%
PF-06685249				AMPK α1β1γ1, EC₅₀: 12 nM				98.32%
Ampkinone			AMPK					99.28%
MT 63-78			AMPK, EC₅₀: 25 μM					98.50%
SAMS			AMPK					99.88%
YLF-466D			AMPK					98.41%
Gomisin J			AMPK					99.84%
3α-Hydroxymogrol			AMPK					99.88%
AMPK activator 1			AMPK, EC₅₀: 0.1 μM					98.53%
AMPK-IN-1							AMPK α2β2γ1, EC₅₀: 551 nM
AMPK activator 2 hydrochloride			AMPK					99.65%
IQZ23			AMPK
LRRK2-IN-8	NUAK1, IC₅₀: 10-100 nM
Kazinol B			AMPK
AMPK activator 9					AMPK α2β1γ1, EC₅₀: 1.1 μM
AMPK activator 8				AMPK α1β1γ1, EC₅₀: 11 nM	AMPK α2β1γ1, EC₅₀: 27 nM	AMPK α1β2γ1, EC₅₀: 4 nM	AMPK α2β2γ1, EC₅₀: 2 nM
AMPK activator 10			AMPK
Etilefrine			AMPK
Tanshinol borneol ester			AMPK
AMPK activator 2			AMPK
LRRK2/NUAK1/TYK2-IN-1	NUAK1
PF-06679142				AMPK α1β1γ1, EC₅₀: 22 nM
ZLN024				AMPK α1β1γ1, EC₅₀: 0.42 μM	AMPK α2β1γ1, EC₅₀: 0.95 μM		AMPK α2β2γ1, EC₅₀: 0.13 μM

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