2. Anti-infection
  3. Influenza Virus
  4. 3-Azaspiro[5.5]undecane hydrochloride

3-Azaspiro[5.5]undecane hydrochloride  (Synonyms: 4,4-Pentamethylenepiperidine hydrochloride)

Cat. No.: HY-107755 Purity: ≥97.0%
COA Handling Instructions

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3-Azaspiro[5.5]undecane (4,4-Pentamethylenepiperidine) hydrochloride is an inhibitor targeting the WT influenza A virus M2 (A/M2), with an IC50 of 1 μM.

For research use only. We do not sell to patients.

3-Azaspiro[5.5]undecane hydrochloride Chemical Structure

3-Azaspiro[5.5]undecane hydrochloride Chemical Structure

CAS No. : 1125-01-5

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3-Azaspiro[5.5]undecane hydrochloride Related Antibodies

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Description

3-Azaspiro[5.5]undecane (4,4-Pentamethylenepiperidine) hydrochloride is an inhibitor targeting the WT influenza A virus M2 (A/M2), with an IC50 of 1 μM[1].

IC50 & Target

IC50: 1 μM (influenza A virus M2)[1]
Molecular Weight

189.73

Formula

C10H20ClN
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

[H]Cl.C12(CCNCC2)CCCCC1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (527.06 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.2706 mL 26.3532 mL 52.7065 mL
5 mM 1.0541 mL 5.2706 mL 10.5413 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥97.0%

COA (247 KB) HNMR (117 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 5.2706 mL 26.3532 mL 52.7065 mL 131.7662 mL
5 mM 1.0541 mL 5.2706 mL 10.5413 mL 26.3532 mL
10 mM 0.5271 mL 2.6353 mL 5.2706 mL 13.1766 mL
15 mM 0.3514 mL 1.7569 mL 3.5138 mL 8.7844 mL
20 mM 0.2635 mL 1.3177 mL 2.6353 mL 6.5883 mL
25 mM 0.2108 mL 1.0541 mL 2.1083 mL 5.2706 mL
30 mM 0.1757 mL 0.8784 mL 1.7569 mL 4.3922 mL
40 mM 0.1318 mL 0.6588 mL 1.3177 mL 3.2942 mL
50 mM 0.1054 mL 0.5271 mL 1.0541 mL 2.6353 mL
60 mM 0.0878 mL 0.4392 mL 0.8784 mL 2.1961 mL
80 mM 0.0659 mL 0.3294 mL 0.6588 mL 1.6471 mL
100 mM 0.0527 mL 0.2635 mL 0.5271 mL 1.3177 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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3-Azaspiro[5.5]undecane hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

3-Azaspiro[5.5]undecane1125-01-54,4-PentamethylenepiperidineInfluenza VirusInhibitorinhibitorinhibit

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