2. Immunology/Inflammation
  3. Toll-like Receptor (TLR)
  4. 5-Chloroisoquinoline

5-Chloroisoquinoline (compound 42) is an inhibitor of SARM1 (Sterile alpha and toll/interleukin receptor (TIR) motif containing protein 1), an enzyme involved in axon degeneration that catalyzes multiple activities through a ternary complex mechanism. 5-Chloroisoquinoline can be used in the study of neurodegenerative diseases or axon degeneration.

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5-Chloroisoquinoline Chemical Structure

5-Chloroisoquinoline Chemical Structure

CAS No. : 5430-45-5

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5-Chloroisoquinoline Related Antibodies

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Description

5-Chloroisoquinoline (compound 42) is an inhibitor of SARM1 (Sterile alpha and toll/interleukin receptor (TIR) motif containing protein 1), an enzyme involved in axon degeneration that catalyzes multiple activities through a ternary complex mechanism. 5-Chloroisoquinoline can be used in the study of neurodegenerative diseases or axon degeneration[1].

IC50 & Target

SARM1
Molecular Weight

163.60

Formula

C9H6ClN
CAS No.
Appearance

Solid

SMILES

ClC1=CC=CC2=CN=CC=C21
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
Purity & Documentation
References
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5-Chloroisoquinoline Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5-Chloroisoquinoline5430-45-5Toll-like Receptor (TLR)Inhibitorinhibitorinhibit

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