2. GPCR/G Protein Neuronal Signaling
  3. Melatonin Receptor
  4. 5-MCA-NAT

5-MCA-NAT is a melatonin agonist that may target the melatoninMT3 receptor. 5-MCA-NAT can contract the colonic band in a concentration-dependent manner and reduce intraocular pressure (IOP) in glaucomatous monkey eyes, inhibiting the increase in IOP.

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5-MCA-NAT Chemical Structure

5-MCA-NAT Chemical Structure

CAS No. : 190277-13-5

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5-MCA-NAT Related Antibodies

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Description

5-MCA-NAT is a melatonin agonist that may target the melatoninMT3 receptor. 5-MCA-NAT can contract the colonic band in a concentration-dependent manner and reduce intraocular pressure (IOP) in glaucomatous monkey eyes, inhibiting the increase in IOP[1][2].

IC50 & Target

Melatonin MT3 receptor[1]
Molecular Weight

275.30

Formula

C14H17N3O3
CAS No.
SMILES

O=C(NC1=CC2=C(NC=C2CCNC(C)=O)C=C1)OC
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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5-MCA-NAT Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5-MCA-NAT190277-13-5Melatonin ReceptorColon contractionintraocular pressureIPOglaucomaInhibitorinhibitorinhibit

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HY-101303
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