2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. 7-(4-Hydroxy-3-methoxyphenyl)-1-phenylhept-4-en-3-one

7-(4-Hydroxy-3-methoxyphenyl)-1-phenylhept-4-en-3-one 

Cat. No.: HY-N8976
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7-(4-Hydroxy-3-methoxyphenyl)-1-phenylhept-4-en-3-one is a inhibitor of prostaglandin biosynthesis.

For research use only. We do not sell to patients.

7-(4-Hydroxy-3-methoxyphenyl)-1-phenylhept-4-en-3-one Chemical Structure

7-(4-Hydroxy-3-methoxyphenyl)-1-phenylhept-4-en-3-one Chemical Structure

CAS No. : 79559-60-7

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7-(4-Hydroxy-3-methoxyphenyl)-1-phenylhept-4-en-3-one Related Antibodies

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Description

7-(4-Hydroxy-3-methoxyphenyl)-1-phenylhept-4-en-3-one is a inhibitor of prostaglandin biosynthesis[1].

Cellular Effect
Cell Line Type Value Description References
B16 IC50
10 μM
Compound: 2
Inhibition of melanogenesis in theophylline-stimulated mouse B16-4A5 cells after 72 hrs
Inhibition of melanogenesis in theophylline-stimulated mouse B16-4A5 cells after 72 hrs
[PMID: 19615910]
B16-4A5 IC50
60 μM
Compound: 2
Inhibition of theophylline-stimulated mouse B16-4A5 cell proliferation assessed as cell viability after 68 hrs by WST8 assay
Inhibition of theophylline-stimulated mouse B16-4A5 cell proliferation assessed as cell viability after 68 hrs by WST8 assay
[PMID: 19615910]
IMR-32 IC50
0.1 μM
Compound: 2
Antiproliferative activity against human IMR-32 cells assessed as reduction in cell viability after 48 hrs by MTT assay
Antiproliferative activity against human IMR-32 cells assessed as reduction in cell viability after 48 hrs by MTT assay
[PMID: 33587631]
MCF7 IC50
20.4 μM
Compound: 2
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay
[PMID: 33587631]
MCF7 IC50
3.9 μM
Compound: 2
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay
[PMID: 33587631]
RAW264.7 IC50
0.6 μM
Compound: 37
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production incubated for 20 hrs by Griess reagent based microplate reader analysis
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production incubated for 20 hrs by Griess reagent based microplate reader analysis
[PMID: 33422907]
U2OS IC50
10.7 μM
Compound: 2
Antiproliferative activity against human U2OS cells assessed as reduction in cell viability after 72 hrs by MTT assay
Antiproliferative activity against human U2OS cells assessed as reduction in cell viability after 72 hrs by MTT assay
[PMID: 33587631]
Molecular Weight

310.39

Formula

C20H22O3
CAS No.
SMILES

O=C(/C=C/CCC1=CC=C(O)C(OC)=C1)CCC2=CC=CC=C2
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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7-(4-Hydroxy-3-methoxyphenyl)-1-phenylhept-4-en-3-one Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

7-(4-Hydroxy-3-methoxyphenyl)-1-phenylhept-4-en-3-one79559-60-7Endogenous MetaboliteInhibitorinhibitorinhibit

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