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  2. Disease Research Fields Plants Terpenoids
  3. Taxaceae Cancer
  4. Taxus cuspidata Siebold & Zucc.
  5. 7-Xylosyl-10-Deacetyltaxol C

7-Xylosyl-10-Deacetyltaxol C  (Synonyms: 7-Xylosyl-10-Deacetylpaclitaxel C)

Cat. No.: HY-N7777
Handling Instructions

7-Xylosyl-10-Deacetyltaxol C (7-Xylosyl-10-Deacetylpaclitaxel C) is a paclitaxel derivative derived from T. cuspidate. 7-Xylosyl-10-Deacetyltaxol C has anti-tumor activity and inhibits the growth of S180 sarcoma.

For research use only. We do not sell to patients.

7-Xylosyl-10-Deacetyltaxol C Chemical Structure

7-Xylosyl-10-Deacetyltaxol C Chemical Structure

CAS No. : 90332-65-3

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Description

7-Xylosyl-10-Deacetyltaxol C (7-Xylosyl-10-Deacetylpaclitaxel C) is a paclitaxel derivative derived from T. cuspidate. 7-Xylosyl-10-Deacetyltaxol C has anti-tumor activity and inhibits the growth of S180 sarcoma[1].

Cellular Effect
Cell Line Type Value Description References
A2780 IC50
1.5 μM
Compound: 11
Antiproliferative activity against human A2780 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human A2780 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
[PMID: 25682561]
A549 IC50
0.64 μM
Compound: 11
Antiproliferative activity against human A549/CDDP cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human A549/CDDP cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
[PMID: 25682561]
A549 IC50
19 μM
Compound: 11
Antiproliferative activity against human A549 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human A549 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
[PMID: 25682561]
HCT-8 IC50
8.5 μM
Compound: 11
Antiproliferative activity against human HCT8 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human HCT8 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
[PMID: 25682561]
HeLa IC50
0.05 μM
Compound: 25
Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 72 hrs by WST-8 dye based assay
Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 72 hrs by WST-8 dye based assay
[PMID: 28240909]
HepG2 IC50
> 25 μM
Compound: 11
Antiproliferative activity against human HepG2 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human HepG2 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
[PMID: 25682561]
MCF7 IC50
> 25 μM
Compound: 11
Antiproliferative activity against human MCF7 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human MCF7 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
[PMID: 25682561]
NIH3T3 IC50
> 25 μM
Compound: 11
Antiproliferative activity against mouse NIH/3T3 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
Antiproliferative activity against mouse NIH/3T3 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
[PMID: 25682561]
SW480 IC50
> 25 μM
Compound: 11
Antiproliferative activity against human SW480 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human SW480 cells assessed as growth inhibition after 48 hrs by sulforhodamine B assay
[PMID: 25682561]
Molecular Weight

938.02

Formula

C49H63NO17

CAS No.
SMILES

CC(O[C@]([C@@]1([H])C[C@@H]2O[C@@](OC[C@H]3O)([H])[C@@H]([C@H]3O)O)(CO1)[C@]([C@@H]([C@@](C4(C)C)(C[C@@H]5OC([C@H](O)[C@H](C6=CC=CC=C6)NC(CCCCC)=O)=O)O)OC(C7=CC=CC=C7)=O)([H])[C@@]2(C([C@@H](C4=C5C)O)=O)C)=O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
7-Xylosyl-10-Deacetyltaxol C
Cat. No.:
HY-N7777
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