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  3. 8α-Hydroxyhirsutinolide

8α-Hydroxyhirsutinolide is a sesquiterpene lactone. 8α-Hydroxyhirsutinolide inhibits TNF-α-induced NF-κB activity (IC50: 1.9 μM) and NO production. 8α-Hydroxyhirsutinolide can be isolated from Vernonia cinerea.

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8α-Hydroxyhirsutinolide Chemical Structure

8α-Hydroxyhirsutinolide Chemical Structure

CAS No. : 1394156-45-6

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Description

8α-Hydroxyhirsutinolide is a sesquiterpene lactone. 8α-Hydroxyhirsutinolide inhibits TNF-α-induced NF-κB activity (IC50: 1.9 μM) and NO production. 8α-Hydroxyhirsutinolide can be isolated from Vernonia cinerea[1].

Molecular Weight

296.32

Formula

C15H20O6

CAS No.
SMILES

OCC1=C2/C(OC1=O)=C\[C@@]3(O[C@]([C@@H](C[C@@H]2O)C)(CC3)O)C

Structure Classification
Initial Source
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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8α-Hydroxyhirsutinolide
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HY-N9699
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