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Anitrazafen is a topically effective antiinflammatory agent.

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Anitrazafen Chemical Structure

Anitrazafen Chemical Structure

CAS No. : 63119-27-7

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Description

Anitrazafen is a topically effective antiinflammatory agent.

In Vivo

Anitrazafen is a topically effective antiinflammatory agent. The disposition of 14C in normal and in bile-duct cannulated rats after oral administration of a single dose of 25 mg/kg of [3-14C]Anitrazafen shows the drug to be well absorbed from the gastro-intestinal tract and biliary excretion to be the major route of elimination of drug and/or metabolites. Plasma concentrations of total 14C after subcutaneous administration of [3-14C]Anitrazafen in corn oil solution are about one half those found after oral administration[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

307.35

Formula

C18H17N3O2
CAS No.
SMILES

CC1=NC(C2=CC=C(OC)C=C2)=C(C3=CC=C(OC)C=C3)N=N1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Animal Administration
[1]

Male albino rats (200 to 250 g) are fasted for 24 h before experiment. [3-14C]Anitrazafen (25 mg/kg) is administered orally to twelve rats. At specific times after dosing, three animals are killed by decapitation and samples of blood and appropriate tissues are removed. Duplicate weighed samples of blood and each tissue are removed for 14C assay[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
References
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Anitrazafen Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anitrazafen63119-27-7LY 122512LY122512LY-122512OthersInhibitorinhibitorinhibit

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