CP-060 

CP-​060 is a potent Ca²⁺ antagonist, inhibits Ca²⁺ overload and possesses antioxidant and cardioprotective activities.

CP-​060 (0.5, 5 μM) inhibits rabbit LDL oxidation induced by soybean lipoxygenase by 12.9% and 3.0%, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

CP-​060 (100 mg/kg, i.v.) increases the coronary blood flow by 96% in anesthetized dogs^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

542.73

C₃₀H₄₂N₂O₅S

180090-15-7

O=C1N(CCCN(CCOC2=CC=C(OCO3)C3=C2)C)C(C4=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C4)SC1

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Kato T, et al. Novel calcium antagonists with both calcium overload inhibition and antioxidant activity. 1. 2-(3, 5-di-tert-butyl-4-hydroxyphenyl)-3-(aminopropyl)thiazolidinones. J Med Chem. 1998 Oct 22;41(22):4309-16.  [Content Brief]

  [2]. Kato T, et al. Novel calcium antagonists with both calcium overload inhibition and antioxidant activity. 2. Structure-activity relationships of thiazolidinone derivatives. J Med Chem. 1999 Aug 12;42(16):3134-46.  [Content Brief]