2. MAPK/ERK Pathway Stem Cell/Wnt
  3. ERK
  4. ERK2 IN-1

ERK2 IN-1 is a selective ERK2 inhibitor with an IC50 of 7 nM.

For research use only. We do not sell to patients.

ERK2 IN-1 Chemical Structure

ERK2 IN-1 Chemical Structure

CAS No. : 1093061-47-2

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ERK2 IN-1 Related Antibodies

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Description

ERK2 IN-1 is a selective ERK2 inhibitor with an IC50 of 7 nM[1].

IC50 & Target[1]

ERK2

7 nM (IC50)

In Vitro

ERK1/2 IN-1 (Compound 28) maintains good ERK enzymatic activity (ERK IC50=7 nM) and cellular activity in BRAF/KRAS mutant wildtype cancer cell lines (HT-29/Caspase IC50=118/80 nM)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

ERK2 IN-1 Related Antibodies
Molecular Weight

647.76

Formula

C36H34FN7O2S
CAS No.
SMILES

FC1=CC=C(C2=NNC3=C2C=C(NC([C@@]4(SC)CN(CC(N5CCC(C6=CC=C(C7=NC=CC=N7)C=C6)=CC5)=O)CC4)=O)C=C3)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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ERK2 IN-1 Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ERK2 IN-11093061-47-2ERKExtracellular signal regulated kinasesInhibitorinhibitorinhibit

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ERK2 IN-1
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HY-112300
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