2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. sn-Glycerol 3-phosphate

sn-Glycerol 3-phosphate is produced by cytosolic glycerol 3-phosphate dehydrogenase pathway through the reduction of dihydroxyacetone phosphate using NADH formed during glycolysis.

The free form of the compound is prone to instability, it is advisable to consider the stable salt form (sn-Glycerol 3-phosphate lithium) that retains the same biological activity.

For research use only. We do not sell to patients.

sn-Glycerol 3-phosphate Chemical Structure

sn-Glycerol 3-phosphate Chemical Structure

CAS No. : 17989-41-2

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Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
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sn-Glycerol 3-phosphate Related Antibodies

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Description

sn-Glycerol 3-phosphate is produced by cytosolic glycerol 3-phosphate dehydrogenase pathway through the reduction of dihydroxyacetone phosphate using NADH formed during glycolysis.

IC50 & Target

Human Endogenous Metabolite

 

Molecular Weight

172.07

Formula

C3H9O6P
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O[C@H](CO)COP(O)(O)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 125 mg/mL (726.45 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.8116 mL 29.0579 mL 58.1159 mL
5 mM 1.1623 mL 5.8116 mL 11.6232 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 25 mg/mL (145.29 mM); Clear solution; Need ultrasonic and warming

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥98.0%

COA (245 KB) HNMR (246 KB) MS (206 KB) Elemental Analysis Report (103 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 5.8116 mL 29.0579 mL 58.1159 mL 145.2897 mL
5 mM 1.1623 mL 5.8116 mL 11.6232 mL 29.0579 mL
10 mM 0.5812 mL 2.9058 mL 5.8116 mL 14.5290 mL
15 mM 0.3874 mL 1.9372 mL 3.8744 mL 9.6860 mL
20 mM 0.2906 mL 1.4529 mL 2.9058 mL 7.2645 mL
25 mM 0.2325 mL 1.1623 mL 2.3246 mL 5.8116 mL
30 mM 0.1937 mL 0.9686 mL 1.9372 mL 4.8430 mL
40 mM 0.1453 mL 0.7264 mL 1.4529 mL 3.6322 mL
50 mM 0.1162 mL 0.5812 mL 1.1623 mL 2.9058 mL
60 mM 0.0969 mL 0.4843 mL 0.9686 mL 2.4215 mL
80 mM 0.0726 mL 0.3632 mL 0.7264 mL 1.8161 mL
100 mM 0.0581 mL 0.2906 mL 0.5812 mL 1.4529 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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sn-Glycerol 3-phosphate Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

sn-Glycerol 3-phosphate17989-41-2Endogenous MetaboliteInhibitorinhibitorinhibit

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