1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. LysoPC(14:0/0:0)

LysoPC(14:0/0:0)  (Synonyms: 14:0 Lyso PC; 1-myristoyl-sn-glycero-3-phosphatidylcholine)

Cat. No.: HY-113123 Purity: 98.06%
COA Handling Instructions

LysoPC(14:0/0:0) is a lysophospholipid (LyP). It is a monoglycerophospholipid in which a phosphorylcholine moiety occupies a glycerol substitution site. LysoPC(14:0/0:0) has potent antispasmodic effect.

For research use only. We do not sell to patients.

LysoPC(14:0/0:0) Chemical Structure

LysoPC(14:0/0:0) Chemical Structure

CAS No. : 20559-16-4

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5 mg USD 50 In-stock
10 mg USD 70 In-stock
25 mg USD 130 In-stock
50 mg USD 210 In-stock
100 mg USD 320 In-stock
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Other Forms of LysoPC(14:0/0:0):

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Description

LysoPC(14:0/0:0) is a lysophospholipid (LyP). It is a monoglycerophospholipid in which a phosphorylcholine moiety occupies a glycerol substitution site. LysoPC(14:0/0:0) has potent antispasmodic effect[1].

IC50 & Target

Human Endogenous Metabolite

 

In Vivo

Of the saturated fatty acid-containing L-α-lysolecithins (LPC), palmitoyl-LPC shows the strongest antispasmodic effect against acetylcholine- or histamine-induced guinea pig ileum contraction; the order of potency of the others is (LysoPC(14:0/0:0)) myristoyl- > stearoyl-, lauroyl- > decanoyl-LPC. Incorporation of a cis-double bond into the C18 fatty acid chain of LPC resulted in a slight decrease of the antispasmodic effect[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

467.58

Formula

C22H46NO7P

CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

CCCCCCCCCCCCCC(OC[C@@H](O)COP(OCC[N+](C)(C)C)([O-])=O)=O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

Ethanol : 50 mg/mL (106.93 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1387 mL 10.6934 mL 21.3867 mL
5 mM 0.4277 mL 2.1387 mL 4.2773 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

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g

Dosing volume
(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 98.06%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
Ethanol 1 mM 2.1387 mL 10.6934 mL 21.3867 mL 53.4668 mL
5 mM 0.4277 mL 2.1387 mL 4.2773 mL 10.6934 mL
10 mM 0.2139 mL 1.0693 mL 2.1387 mL 5.3467 mL
15 mM 0.1426 mL 0.7129 mL 1.4258 mL 3.5645 mL
20 mM 0.1069 mL 0.5347 mL 1.0693 mL 2.6733 mL
25 mM 0.0855 mL 0.4277 mL 0.8555 mL 2.1387 mL
30 mM 0.0713 mL 0.3564 mL 0.7129 mL 1.7822 mL
40 mM 0.0535 mL 0.2673 mL 0.5347 mL 1.3367 mL
50 mM 0.0428 mL 0.2139 mL 0.4277 mL 1.0693 mL
60 mM 0.0356 mL 0.1782 mL 0.3564 mL 0.8911 mL
80 mM 0.0267 mL 0.1337 mL 0.2673 mL 0.6683 mL
100 mM 0.0214 mL 0.1069 mL 0.2139 mL 0.5347 mL
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Product Name:
LysoPC(14:0/0:0)
Cat. No.:
HY-113123
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