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  5. Aiphanes aculeata Willd

Aiphanes aculeata Willd

Aiphanes aculeata Willd (1):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-152120
    (±)-Aiphanol 578020-29-8
    (±)-Aiphanol is a newly discovered stilbenolignan analog. (±)-Aiphanol exhibits significant anti-inflammatory activity, acting through inhibition of COX-1 and COX-2. The inhibitory effect on COX-1 (IC50 = 1.9 μM) is particularly strong, while the effect on COX-2 (IC50= 9.9 μM) is relatively weak.(±)-Aiphanol effectively inhibits VEGFR2/KDR/Flk-1 (IC50=0.92 µM). (±)-Aiphanol blocks angiogenesis and promotes apoptosis through inhibition of VEGFR2/KDR/Flk-1 and COX2 activity. (±)-Aiphanol is orally active.
    (±)-Aiphanol