2. Natural Products
  3. Plants
  4. Pinaceae
  5. Pinus lambertiana Douglas

Pinus lambertiana Douglas

Pinus lambertiana Douglas (1):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-127057
    Lambertianic acid 4966-13-6
    Lambertianic acid is a bioactive diterpene with anti-allergic, antibacterial and anticancer activities. Lambertianic acid decreases androgen receptor protein levels, cellular and secretory levels of prostate-specific antigen. Lambertianic acid also suppresses cell proliferation by inducing G1 arrest, downregulating CDK4/6 and cyclin D1, activating p53, p21 and p27. Lambertianic acid induces Apoptosis and the expression of related proteins, including cleaved caspase-3/9, c-PARP and BAX, and inhibited BCl-2. Lambertianic acid is promising for research of prostate cancer.
    Lambertianic acid