2. Signaling Pathways
  3. Apoptosis
  4. Caspase
  5. Caspase 8 Isoform
  6. Caspase 8 Inducer

Caspase 8 Inducer

Caspase 8 Inducer (1):

Cat. No. Product Name Effect Purity
  • HY-110077
    API-1
    		Inducer 99.62%
    API-1 is a potent selective Akt/PKB inhibitor that reduces the level of phosphorylated Akt (IC50 = 0.8 μM). API-1 binds to the PH domain and inhibits Akt membrane translocation. API-1 induces c-FLIP degradation. API-1 reduces cell proliferation and induces apoptosis. API-1 decreases tumor growth in mouse xenograft model.