2. Signaling Pathways
  3. Membrane Transporter/Ion Channel
  4. EAAT
  5. EAAT Isoform
  6. EAAT Modulator

EAAT Modulator

EAAT Modulators (2):

Cat. No. Product Name Effect Purity
  • HY-W585874
    Nε-(Carboxyethyl)lysine
    		Modulator
    Nε-(Carboxyethyl)lysine is an advanced glycation end product (AGE). Nε-(Carboxyethyl)lysine causes cross-linking between proteins, affects the structure and function of proteins, and leads to protein denaturation. Nε-(Carboxyethyl)lysine binds to RAGE receptors, affects cell signaling, regulates processes such as inflammatory response, cell proliferation and apoptosis. Nε-(Carboxyethyl)lysine affects glutamate transporter, reduces glutamate uptake and S100B protein secretion, affects neurotransmission in the nervous system, and exhibits diabetic-related neurotoxicity.
  • HY-162454
    DA-023
    		Modulator
    DA-023 (Compound 4) is a selective positive allosteric modulator (PAM) of EAAT2 with an EC50 value of 1 nM.