2. Signaling Pathways
  3. Epigenetics
  4. Glycosyltransferase

Glycosyltransferase

Glycosyltransferases (GTs) are key enzymes in the biosynthesis of ginsenosides, which can catalyze the transfer of glycans from donor molecules to acceptor molecules, and form a variety of biologically active glycoside compounds.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-107366
    SGN-2FF
    		Inhibitor ≥98.0%
    SGN-2FF is a potent and orally active inhibitor of fucosylation, directly inhibits fucosyltransferase activity. SGN-2FF possesses antitumor activity.
    SGN-2FF
  • HY-139056
    SU0268
    		Inhibitor 99.96%
    SU0268 is a potent and specific inhibitor of 8-Oxoguanine DNA glycosylase 1 (OGG1). SU0268 regulates inflammatory responses during Pseudomonas aeruginosa infection.
    SU0268
  • HY-120872
    AJS1669 free acid
    		Activator 99.15%
    AJS1669 free acid is a potent and orally available glycogen synthase (GS) activator. AJS1669 improves glucose metabolism and reduces body fat mass in mice[1].
    AJS1669 free acid
  • HY-E70047
    alpha-1,4-Galactosyltransferase (LgtC)
    alpha-1,4-Galactosyltransferase (LgtC) (A4GALT) is a glycosphingolipid-specific glycosyltransferase. alpha-1,4-Galactosyltransferase (LgtC) transfers a galactose to the alpha-1,4 position of lactosylceramide to form globotriaosylceramide. alpha-1,4-Galactosyltransferase (LgtC) can be used for the synthesis of P1 blood group antigens.
    alpha-1,4-Galactosyltransferase (LgtC)
  • HY-E70044
    beta-1, 3-N-Acetylhexaminyltransferase (LgtA)
    beta-1, 3-N-Acetylhexaminyltransferase (LgtA) is a glycosyltransferase, is often used in biochemical studies. beta-1, 3-N-Acetylhexaminyltransferase (LgtA) catalyzes the transfer of N-acetylglucosamine from UDP-GlcNAc to N-acetyllactosamine and lactose.
    beta-1, 3-N-Acetylhexaminyltransferase (LgtA)
  • HY-169084
    ST-IN-1
    		Inhibitor
    ST-IN-1 (compound (R)-1) is a selective ST inhibitor (Ki=70 nM, rat a-2,6-ST; Ki=19 nM, hST6GAL1) with antitumor activity. ST-IN-1 inhibits tumor growth and metastasis by delipidating the surface of tumor cells.
    ST-IN-1
  • HY-E70287
    ST6 Sialyltransferase 5
    ST6 Sialyltransferase 5 (EC:2.4.3.3, ST6GALNAC5, SIAT7E, ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5) transfers a sialic acid to N-acetylgalactosamine (GalNAc) residues. ST6 Sialyltransferase 5 is a bio-marker in cervical screening samples.
    ST6 Sialyltransferase 5
  • HY-E70160
    Protein O-Fucosyltransferase 1
    Protein O-Fucosyltransferase 1 (EC:2.4.1.221; POFUT1) is a Glycosyltransferase containing the cysteine-rich motifs as the acceptor sugar and GDP-fucose as the donor.
    Protein O-Fucosyltransferase 1
  • HY-157461
    Glycation-IN-1
    Glycation-IN-1 (Compound 3) is an inhibitor of glycosylation reactions, which has a strong inhibitory effect on the synthesis of initial, intermediate, and final products of glycosylation reactions. Glycion-IN-1 can be used in the research of various chronic diseases, such as diabetes, immune inflammation, cardiovascular diseases and neurodegenerative diseases.
    Glycation-IN-1
  • HY-147960
    Glycosyltransferase-IN-1
    		Inhibitor
    Glycosyltransferase-IN-1 (compound 5m) is a potent glycosyltransferase inhibitor, with an IC50 of 82.8 μM. Glycosyltransferase-IN-1 shows antibacterial activity, with MIC values of 6 μg/mL for MSSA, MRSA, B. subtilis and 12 μg/mL for E. coli.
    Glycosyltransferase-IN-1
Cat. No. Product Name / Synonyms Application Reactivity