2. Signaling Pathways
  3. Anti-infection
  4. HIV
  5. HIV-1 Isoform
  6. HIV-1 Antagonist

HIV-1 Antagonist

HIV-1 Antagonists (2):

Cat. No. Product Name Effect Purity
  • HY-139989
    NBD-14270
    		Antagonist 98.47%
    NBD-14270, a pyridine analogue, is a potent HIV-1 entry antagonist with an IC50 of 180 nM against 50 HIV-1 Env-pseudotyped viruses. NBD-14270 binds to HIV-1 gp120 and shows potent antiviral activity. NBD-14270 shows low cytotoxicity (CC50>100 μM).
  • HY-139985
    NBD-14189
    		Antagonist 99.84%
    NBD-14189 is a potent HIV-1 entry antagonist with an IC50 of 89 nM against the HIV-1HXB2 pseudovirus. NBD-14189 binds to HIV-1 gp120 and shows potent antiviral activity (EC50<200 nM).