2. Signaling Pathways
  3. Cytoskeleton
  4. Integrin
  5. Integrin Isoform
  6. Integrin Agonist

Integrin Agonist

Integrin Agonists (4):

Cat. No. Product Name Effect Purity
  • HY-13306
    Pyrintegrin
    		Agonist 99.41%
    Pyrintegrin is an β1-integrin agonist and a 2,4-disubstituted pyrimidine that promotes embryonic stem cells survival. Pyrintegrin enhances cell-extracellular matrix (ECM) adhesion-mediated integrin signaling. Pyrintegrin can be used as a podocyte-protective agent and has robustly adipogenic.
  • HY-164768
    LT25
    		Agonist 98.73%
    LT25 (compound 17) is a agonist of α5β1 integrin with EC50 value of 9.9 nM.
  • HY-15701
    Leukadherin-1
    		Agonist ≥98.0%
    Leukadherin-1, a specific agonist of the leukocyte surface integrin CD11b/CD18, increases CD11b/CD18-dependent cell adhesion to fibrinogen with an EC50 of 4 μM. Leukadherin-1 enhances leukocyte adhesion to ligands (such as ICAM-1) and vascular endothelium and thus reduces leukocyte transendothelial migration and influx to the injury sites. Leukadherin-1 suppresses innate inflammatory signaling.
  • HY-139702
    α5β1 integrin agonist-1
    		Agonist 99.96%
    α5β1 integrin agonist-1, acting as α5β1 integrin agonist, is able to selectively deliver 5-FU into tumor cells, successfully leading to cancer cell death.