2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. MMP
  5. MMP-17 Isoform
  6. MMP-17 Inhibitor

MMP-17 Inhibitor

MMP-17 Inhibitor (1):

Cat. No. Product Name Effect Purity
  • HY-110397
    KP-457
    		Inhibitor 99.18%
    KP-457 is a selective a disintegrin and metalloproteinase 17 (ADAM17) inhibitor, with higher selectivity for ADAM17 than for other MMPs and ADAM10, and IC50s are 11.1 nM (ADAM17), 748 nM (ADAM10), 717 nM (MMP2), 9760 nM (MMP3), 2200 nM (MMP8), 5410 nM (MMP9), 930 nM (MMP13), 2140 nM (MMP14), and 7100 nM (MMP17), respectively.