2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-145533
    3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid
    3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid (KDN) is a sialic acid. 3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid protects the oligo/(poly)sialyl chains from exosialidases at nonreducing terminal, and plays a role in egg activation of salmonid fish. 3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid is abundant in fetal cord red blood cells and malignant human ovarian cancer cells.
    3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid
  • HY-136648AR
    2'-Deoxyadenosine-5'-triphosphate (trisodium) (Standard)
    2'-Deoxyadenosine-5'-triphosphate trisodium (Standard) (dATP trisodium (Standard)) is the analytical standard of 2'-Deoxyadenosine-5'-triphosphate trisodium (HY-136648A). This product is intended for research and analytical applications. 2'-Deoxyadenosine-5'-triphosphate trisodium (dATP trisodium) is a nucleotide used in cells for DNA synthesis (or replication), as a substrate of DNA polymerase.
    2'-Deoxyadenosine-5'-triphosphate (trisodium) (Standard)
  • HY-116865
    Equilenin
    		≥98.0%
    Equilenin is a B-ring unsaturated estrogen and one of the main ingredients in Premarin, a drug commonly used in estrogen replacement therapy. Equilenin can bind to estrogen receptors in the body and exert effects similar to endogenous estrogen. Equilenin can be used in estrogen replacement therapy and breast cancer research.
    Equilenin
  • HY-N1214R
    Squalene (Standard)
    Squalene (Standard) is the analytical standard of Squalene. This product is intended for research and analytical applications. Squalene (Super Squalene) is an intermediate product in the synthesis of cholesterol, and shows several pharmacological properties such as hypolipidemic, hepatoprotective, antiatherosclerotic, cardioprotective, antioxidant, and antitumour activity.
    Squalene (Standard)
  • HY-Y0966R
    Glycine (Standard)
    		99.93%
    Glycine (Standard) is the analytical standard of Glycine. This product is intended for research and analytical applications. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors. Glycine is orally active. Glycine can be used to study cell protection, cancer, neurological diseases, and angiogenesis.
    Glycine (Standard)
  • HY-Y0079S1
    D-Phenylalanine-d8
    		98.28%
    D-Phenylalanine-d8 is the deuterium labeled D-Phenylalanine. D-Phenylalanine is the synthetic dextro isomer of phenylalanine. D-Phenylalanine inhibits biofilm development of Pseudoalteromonas sp. SC2014[1].
    D-Phenylalanine-d<sub>8</sub>
  • HY-100582S
    Ribitol-1-13C
    		99.51%
    Ribitol-1-13C is the 13C labeled Ribitol. Ribitol is a crystalline pentose alcohol formed by the reduction of ribose. Enhancing the flux of D-glucose to the pentose phosphate pathway in Saccharomyces cerevisiae for the production of D-ribose and ribitol.
    Ribitol-1-<sup>13</sup>C
  • HY-113208
    13,14-Dihydro-15-keto Prostaglandin F2α
    		≥99.0%
    13,14-Dihydro-15-keto Prostaglandin F2α (13,14-Dihydro-15-keto-PGF2α) is an endogenous metabolite present in Blood that can be used for the research of Pregnancy.
    13,14-Dihydro-15-keto Prostaglandin F2α
  • HY-W035599
    Ir[p-F(t-Bu)-ppy]3
    Ir[pF(t-Bu)-ppy]3 (Tris(2-(3-tert-butylphenyl)-4-tert-butylpyridine)iridium) is an effective photocatalyst with excellent catalytic activity. Ir[pF(t-Bu)-ppy]3 can promote organic reactions, especially showing significant potential in the synthesis of new organic compounds. Ir[pF(t-Bu)-ppy]3 can be used to develop green chemical processes and reduce the impact of traditional catalysts on the environment. Ir[pF(t-Bu)-ppy]3 also has broad prospects in photoelectrochemical applications.
    Ir[p-F(t-Bu)-ppy]3
  • HY-113081S
    1-Methyladenosine-d3
    1-Methyl Adenosine-d3 is the deuterium labeled 1-Methyladenosine. 1-Methyladenosine is an RNA modification that can serve as a tumor marker, with elevated levels in the body associated with cancer development. Following 1-methyladenosine methylation, upregulation of PPARδ expression regulates cholesterol metabolism and activates Hedgehog signaling pathway, driving liver tumorigenesis.
    1-Methyladenosine-d<sub>3</sub>
  • HY-N0215R
    L-Phenylalanine (Standard)
    L-Phenylalanine (Standard) is the analytical standard of L-Phenylalanine. This product is intended for research and analytical applications. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals.
    L-Phenylalanine (Standard)
  • HY-W012980R
    Isovaleric acid (Standard)
    Isovaleric acid (Standard) is the analytical standard of Isovaleric acid. This product is intended for research and analytical applications. Isovaleric acid is an oral active short-chain fatty acid that inhibits osteoclast differentiation by stimulating AMPK phosphorylation and promotes colonic smooth muscle relaxation by activating the cAMP/PKA pathway. Isovaleric acid can be used in research on skeletal diseases (such as osteoporosis) and intestinal disorders.
    Isovaleric acid (Standard)
  • HY-W015882R
    4-Methylpentanoic acid (Standard)
    4-Methylpentanoic acid (Isocaproic acid) (Standard) is an analytical standard form of 4-Methylpentanoic acid (HY-W015882). This product is intended for research and analytical applications. 4-Methylpentanoic acid is a short chain fatty acid (SCFA).
    4-Methylpentanoic acid (Standard)
  • HY-128736
    L-2-Phosphoglyceric acid
    L-2-Phosphoglyceric acid is an endogenous metabolite.
    L-2-Phosphoglyceric acid
  • HY-125818S1
    Cytidine-5′-triphosphate-d14 disodium
    		98.00%
    Cytidine-5′-triphosphate-d14 (disodium) is the deuterium labeled Cytidine-5'-triphosphate[1]. Cytidine 5′-triphosphate (Cytidine triphosphate;5'-CTP) is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate is an essential biomolecule in the de novo pyrimidine biosynthetic pathway in T. gondii[2].
    Cytidine-5′-triphosphate-d<sub>14</sub> disodium
  • HY-B0617S2
    S-Adenosyl-L-methionine-13C dihydrochloride
    S-Adenosyl-L-methionine-13C (S-Adenosyl methionine-13C) dihydrochloride is the 13C labeled S-Adenosyl-L-methionine (HY-B0617). S-Adenosyl-L-methionine (S-Adenosyl methionine) is an orally active methyl group donor. S-Adenosyl-L-methionine is a dietary supplement with potent antidepressant effects. S-Adenosyl-L-methionine also has anti‑proliferative, pro‑apoptotic and anti‑metastatic roles in cancers. S-Adenosyl-L-methionine has the potential for, cancer, liver disease and osteoarthritis research.
    S-Adenosyl-L-methionine-<sup>13</sup>C dihydrochloride
  • HY-N0708R
    Vanillic acid (Standard)
    Vanillic acid (Standard) is the analytical standard of Vanillic acid. This product is intended for research and analytical applications. Vanillic acid is a flavoring agent found in edible plants and fruits, also found in Angelica sinensis. Vanillic acid inhibits NF-κB activation. Anti-inflammatory, antibacterial, and chemopreventive effects.
    Vanillic acid (Standard)
  • HY-B1008S
    4-Aminobenzoic acid-d4
    		99.53%
    4-Aminobenzoic acid-d4 is the deuterium labeled 4-Aminobenzoic acid. 4-Aminobenzoic acid is an intermediate in the synthesis of folate by bacteria, plants, and fungi.
    4-Aminobenzoic acid-d<sub>4</sub>
  • HY-124177A
    C14 Ceramide (d18:1/14:0)
    		≥99.0%
    C14 Ceramide (d18:1/14:0) is an endogenous ceramide produced by ceramide synthetase 6, which can be used for Parkinson's and diabetes research.
    C14 Ceramide (d18:1/14:0)
  • HY-113254
    13,14-Dihydro-15-keto-PGE2
    13,14-Dihydro-15-keto-PGE2 participates in Bifidobacterium animalis F1-7 to alleviate opioid-induced constipation by 5-HT pathway.
    13,14-Dihydro-15-keto-PGE2
Cat. No. Product Name / Synonyms Application Reactivity