2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W749251
    5-Aminolevulinic acid-13C2,15N hydrochloride
    		≥99.0%
    5-Aminolevulinic acid-13C2,15N (5-ALA-13C2,15N; δ-Aminolevulinic acid-13C2,15N) is 13C- and 15N-labeled 5-Aminolevulinic acid (HY-W000450).
    5-Aminolevulinic acid-<sup>13</sup>C<sub>2</sub>,<sup>15</sup>N hydrochloride
  • HY-W336192
    (3E,8Z,11Z)-3,8,11-Tetradecatrienyl acetate
    (3E,8Z,11Z)-3,8,11-Tetradecatrienyl acetate is a sex pheromone capable of attracting male South American tomato pinworms (Scrobipalpuloides absoluta), which can be isolated from the tomato pest.
    (3E,8Z,11Z)-3,8,11-Tetradecatrienyl acetate
  • HY-41314
    Ethyl 3-methyl-2-butenoate
    		99.54%
    Ethyl 3-methyl-2-butenoate is a volatile compound that can be isolated from sea buckthorn.
    Ethyl 3-methyl-2-butenoate
  • HY-I0746
    3-Aminobenzoic acid
    		99.93%
    3-Aminobenzoic acid (3-ABA) is an orally active anti-inflammatory agent targeting the tight junction (TJ) regulatory pathways in intestinal epithelial cells. 3-Aminobenzoic acid improves intestinal inflammation by enhancing intestinal barrier integrity and reducing epithelial permeability. It can be used in studies related to improving gut health. Additionally, 3-Aminobenzoic acid analogs can act as γ-aminobutyric acid transaminase (GABA-AT) inhibitors, exhibiting anticonvulsant effects.
    3-Aminobenzoic acid
  • HY-108872S1
    Water-17O
    		≥99.0%
    Water-17O is the 17O labeled Water.
    Water-<sup>17</sup>O
  • HY-N0091S
    Hypoxanthine-13C5,15N4
    		≥99.0%
    Hypoxanthine-13C5,15N4 is a 15N-labeled and 13C-labled Dansyl chloride.
    Hypoxanthine-<sup>13</sup>C<sub>5</sub>,<sup>15</sup>N<sub>4</sub>
  • HY-116133
    3-Hydroxystearic acid
    		98.25%
    3-hydroxy Stearic acid is a long-chain saturated fatty acid and can be found in C. pyloridis.
    3-Hydroxystearic acid
  • HY-F0003R
    NADPH (tetrasodium salt) (Standard)
    NADPH tetrasodium salt (Standard) is the analytical standard of NADPH tetrasodium salt (HY-F0003). This product is intended for research and analytical applications. NADPH tetrasodium salt functions as an important cofactor in a variety of metabolic and biosynthetic pathways. NADPH tetrasodium salt plays a vital role in the biosynthesis of agents, chiral alcohols, fatty acids and biopolymers, while also being required for lipid biosynthesis, biomass formation, and cell replication. The demand for NADPH tetrasodium salt is particularly high in proliferating cancer cells, where it acts as a cofactor for the synthesis of nucleotides, proteins, and fatty acids. NADPH tetrasodium salt is also essential for the neutralization of the dangerously high levels of reactive oxygen species (ROS) generated by increased metabolic activity. NADPH tetrasodium salt is an endogenous inhibitor of ferroptosis.
    NADPH (tetrasodium salt) (Standard)
  • HY-Y1373S1
    Cyclohexanecarboxylic acid-d11
    		99.14%
    Cyclohexanecarboxylic acid-d11 is the deuterium labeled Cyclohexanecarboxylic acid[1]. Cyclohexanecarboxylic acid is a Valproate structural analogue with anticonvulsant action[2].
    Cyclohexanecarboxylic acid-d<sub>11</sub>
  • HY-N0905
    Ginsenoside Rh4
    		99.28%
    Ginsenoside Rh4 is a rare saponin obtained from Panax notoginseng. Ginsenoside Rh4 activates Bax, caspase 3, caspase 8, and caspase 9. Ginsenoside Rh4 also induces autophagy.
    Ginsenoside Rh4
  • HY-W012480S
    DL-Tryptophan-d3
    		99.29%
    DL-Tryptophan-d3 is the deuterium labeled DL-Tryptophan. DL-Tryptophan is an endogenous metabolite.
    DL-Tryptophan-d<sub>3</sub>
  • HY-U00264
    2-γ-Linolenoyl-1,3-dilinoleoyl-sn-glycerol
    		≥99.0%
    2-γ-Linolenoyl-1,3-dilinoleoyl-sn-glycerol is a triglyceride.
    2-γ-Linolenoyl-1,3-dilinoleoyl-sn-glycerol
  • HY-17567
    Heparin
    Heparin is a highly sulfated glycosaminoglycan,that is widely used as an injectable anticoagulant, and has the highest negative charge density of any known biological molecule. Heparin significantly inhibits exosome-cell interactions.
    Heparin
  • HY-W040329R
    2'-Deoxyadenosine (Standard)
    2'-Deoxyadenosine (Standard) is the analytical standard of 2'-Deoxyadenosine. This product is intended for research and analytical applications. 2'-Deoxyadenosine is a nucleoside adenosine derivative, pairing with deoxythymidine (T) in double-stranded DNA.
    2'-Deoxyadenosine (Standard)
  • HY-13765R
    6-Thioguanine (Standard)
    6-Thioguanine (Standard) is the analytical standard of 6-Thioguanine. This product is intended for research and analytical applications. 6-Thioguanine (Thioguanine; 2-Amino-6-purinethiol) is an anti-leukemia and immunosuppressant agent, acts as an inhibitor of SARS and MERS coronavirus papain-like proteases (PLpros) and also potently inhibits USP2 activity, with IC50s of 25 μM and 40 μM for Plpros and recombinant human USP2, respectively.
    6-Thioguanine (Standard)
  • HY-D0845R
    Nitrosoglutathione (Standard)
    Nitrosoglutathione (Standard) (GSNO (Standard)) is the analytical standard of Nitrosoglutathione (HY-D0845). This product is intended for research and analytical applications. Nitrosoglutathione (GSNO), a exogenous NO donor and a substrate for rat alcohol dehydrogenase class III isoenzyme, inhibits cerebrovascular angiotensin II-dependent and -independent AT1 receptor responses. x
    Nitrosoglutathione (Standard)
  • HY-113360
    Chenodeoxycholic acid 3-sulfate
    Chenodeoxycholic acid 3-sulfate is a bile acid. Chenodeoxycholic acid 3-sulfate level corresponds closely with the extent of hepatic dysfunction.
    Chenodeoxycholic acid 3-sulfate
  • HY-B0586R
    Methylcobalamin (Standard)
    Methylcobalamin (Standard) is the analytical standard of Methylcobalamin. This product is intended for research and analytical applications. Methylcobalamin (CH3-B12), a cobalamin, is a form of vitamin B12.
    Methylcobalamin (Standard)
  • HY-Z0833
    Bazedoxifene N-Oxide
    Bazedoxifene N-Oxide is the oxidative degradation product of selective estrogen receptor modulator (SERM) Bazedoxifene.
    Bazedoxifene N-Oxide
  • HY-W013636S3
    2-Ketoglutaric acid-13C
    2-Ketoglutaric acid-13C (Alpha-Ketoglutaric acid-13C) is a 13C labeled 2-Ketoglutaric acid (HY-W013636). 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM).
    2-Ketoglutaric acid-<sup>13</sup>C
Cat. No. Product Name / Synonyms Application Reactivity