2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W013636S3
    2-Ketoglutaric acid-13C
    2-Ketoglutaric acid-13C (Alpha-Ketoglutaric acid-13C) is a 13C labeled 2-Ketoglutaric acid (HY-W013636). 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM).
    2-Ketoglutaric acid-<sup>13</sup>C
  • HY-17556R
    Folinic acid (Standard)
    Folinic acid (Standard) is the analytical standard of Folinic acid. This product is intended for research and analytical applications. Folinic acid (Leucovorin) is a biological folic acid and is generally administered along with Methotrexate (MTX) (HY-14519) as a rescue agent to decrease MTX-induced toxicity.
    Folinic acid (Standard)
  • HY-W016482
    3-(3-Methoxyphenyl)propionic acid
    		98.75%
    3-(3-Methoxyphenyl)propionic acid is an organic acid, naturally occurring human metabolite and excreted in human urine.
    3-(3-Methoxyphenyl)propionic acid
  • HY-A0181S2
    Adenosine monophosphate-d12 dilithium
    Adenosine monophosphate-d12 (AMP-d12) dilithium is deuterium labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction.
    Adenosine monophosphate-d<sub>12</sub> dilithium
  • HY-168762
    C32 Ceramide
    		≥98.0%
    C32 Ceramide is a naturally occurring ceramide that has been found in the stratum corneum of human and nude mouse skin.
    C32 Ceramide
  • HY-139351
    Gibberellins A4/A7
    Gibberellins A4/A7 induces stimulation of tracheid production in the terminal shoot of intact plants is mediated through an increase in the IAA level in the cambial region.
    Gibberellins A4/A7
  • HY-108692S
    Enterolactone-d6
    Enterolactone-d6 is the deuterium labeled Enterolactone. Enterolactone is a bioactive phenolic metabolite known as a mammalian lignan derived from dietary lignans. Enterolactone has estrogenic properties and anti-breast cancer activity[1]. Enterolactone is a radiosensitizer for human breast cancer cell lines through impaired DNA repair and increased apoptosis[2].
    Enterolactone-d<sub>6</sub>
  • HY-N5134S2
    5'-Guanylic acid-15N5 dilithium
    5'-Guanylic acid-15N5 (5'-GMP-15N5 dilithium; 5'-guanosine monophosphate-15N5) dilithium is 15N labeled 5'-Guanylic acid (HY-N5134). 5'-Guanylic acid (5'-GMP) is involved in several metabolic disorders, including the AICA-ribosiduria pathway, adenosine deaminase deficiency, adenine phosphoribosyltransferase deficiency (aprt), and the 2-hydroxyglutric aciduria pathway.
    5'-Guanylic acid-<sup>15</sup>N<sub>5</sub> dilithium
  • HY-118149
    9(S)-HpODE
    		98.0%
    9(S)-HpODE is produced by the action of arachidonate 5-LO on linoleic acid. It can be further metabolized by potato hydroperoxide dehydratase to colneleic acid.
    9(S)-HpODE
  • HY-N13295
    Indole-3-lactate-O-β-D-glucopyranoside
    		99.92%
    Indole-3-lactate-O-β-D-glucopyranoside is an endogenous metabolite that acts as a plant growth regulator.
    Indole-3-lactate-O-β-D-glucopyranoside
  • HY-N5158B
    (5S)-Neosamine C
    (5S)-Neosamine C is an aminocyclic alcohol antibiotic derived from microbial secondary metabolites. (5S)-Neosamine C has a cyclized structure and can be used for biosynthesis of Neomycins (HY-B0470).
    (5S)-Neosamine C
  • HY-113324R
    NADPH (Standard)
    NADPH (Standard) is the analytical standard of NADPH. This product is intended for research and analytical applications. NADPH is a reducing agent in metabolism with a potential for electrosynthesis.
    NADPH (Standard)
  • HY-76542S
    Vitamin D2-d6
    Vitamin D2-d6 is the deuterium labeled Vitamin D2. Vitamin D2 (Ergocalciferol), drived from plant sources or dietary supplements, could be used as supplement of Vitamin D[1][2].
    Vitamin D2-d<sub>6</sub>
  • HY-B1449R
    Uridine (Standard)
    Uridine (Standard) is the analytical standard of Uridine. This product is intended for research and analytical applications.
    Uridine (Standard)
  • HY-B1008R
    4-Aminobenzoic acid (Standard)
    4-Aminobenzoic acid (Standard) is the analytical standard of 4-Aminobenzoic acid. This product is intended for research and analytical applications. 4-Aminobenzoic acid is an intermediate in the synthesis of folic acid by bacteria, plants and fungi.
    4-Aminobenzoic acid (Standard)
  • HY-100551R
    meso-Erythritol (Standard)
    meso-Erythritol (Standard) is the analytical standard of meso-Erythritol. This product is intended for research and analytical applications. meso-Erythritol is a sugar alcohol that occurs naturally in a variety of foods (e.g., pear, watermelon), is 60-80% as sweet as sucrose, and is an approved low-calorie sweetener food additive.
    meso-Erythritol (Standard)
  • HY-12184
    ONO-AE 248
    ONO-AE 248 is a selective EP3 receptor agonist with cardioprotective activity. ONO-AE 248 reduces myocardial infarction size by selectively binding to the EP3α receptor in mice. The cardioprotective effect of ONO-AE 248 is independent of hemodynamic effects. The mechanism of ONO-AE 248 may involve activation of protein kinase C and opening of K(ATP) channels.
    ONO-AE 248
  • HY-15398S
    Vitamin D3-d7
    Vitamin D3-d7 is the deuterium labeled Vitamin D3. Vitamin D3 (Cholecalciferol) is a naturally occuring form of vitamin D. Vitamin D3 induces cell differentiation and prevents proliferation of cancer cells[1][2].
    Vitamin D3-d<sub>7</sub>
  • HY-N7092R
    D-Fructose (Standard)
    D-Fructose (Standard) is the analytical standard of D-Fructose. This product is intended for research and analytical applications. D-Fructose (D(-)-Fructose) is a monosaccharide found in honey, fruits, and other plants. Two D-Fructose molecules can combine to form a disaccharide, sucrose.
    D-Fructose (Standard)
  • HY-19657S
    Oxypurinol-13C,15N2
    Oxypurinol-13C,15N2 is 15N and 13C labeled Oxypurinol (HY-19657). Oxipurinol (Oxipurinol), the major active metabolite of Allopurinol, is an inhibitor of xanthine oxidase. Oxipurinol can be used to regulate blood urate levels and treat gout.
    Oxypurinol-<sub>13</sub>C,<sub>15</sub>N<sub>2</sub>
Cat. No. Product Name / Synonyms Application Reactivity