2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-U00023
    NCX 1000
    NCX 1000 is a liver-specific NO donor compound derived from ursodeoxycholic acid (UDCA).
    NCX 1000
  • HY-N11848R
    D-Glucosamine 6-phosphate (Standard)
    Hyodeoxycholic acid (Standard) is the analytical standard of Hyodeoxycholic acid. This product is intended for research and analytical applications. Hyodeoxycholic acid is a secondary bile acid formed in the small intestine by the gut flora, and acts as a TGR5 (GPCR19) agonist, with an EC50 of 31.6 µM in CHO cells.
    D-Glucosamine 6-phosphate (Standard)
  • HY-W001171S
    3-Hydroxyanthranilic acid-d3
    		99.28%
    3-Hydroxyanthranilic acid-d3 is deuterium-labeled 3-Hydroxyanthranilic acid (HY-W001171).
    3-Hydroxyanthranilic acid-d<sub>3</sub>
  • HY-W016203
    Phenylpyruvic acid sodium
    Phenylpyruvic acid sodium is a endogenous metabolite that participates in the synthesis of 3-phenyllactic acid (PLA) by lactate dehydrogenase.
    Phenylpyruvic acid sodium
  • HY-W001953
    2-Naphthalenemethanol
    		99.47%
    2-Naphthalenemethanol is the metabolite of environmental pollutant 2-methylnaphthalene. 2-Naphthalenemethanol covalently binds to alveolar protein and induces pulmonary toxicity.
    2-Naphthalenemethanol
  • HY-I0301R
    D-(+)-Glucono-1,5-lactone (Standard)
    D-(+)-Glucono-1,5-lactone (Standard) is the analytical standard of D-(+)-Glucono-1,5-lactone. This product is intended for research and analytical applications. D-(+)-Glucono-1,5-lactone is a polyhydroxy (PHA) that is capable of metal chelating, moisturizing and antioxidant activity.
    D-(+)-Glucono-1,5-lactone (Standard)
  • HY-W583317
    sSPhos Pd G2
    		≥98.0%
    sSPhos Pd G2 is a palladium catalyst with excellent cross-coupling reaction activity. sSPhos Pd G2 exhibits efficient catalytic ability in the synthesis of organic molecules and compounds. sSPhos Pd G2 can effectively promote the formation of CC bonds, optimize reaction conditions and increase yields. sSPhos Pd G2 is also used in a variety of transformation reactions, helping researchers develop new materials and compounds.
    sSPhos Pd G2
  • HY-W018324
    5-Hydroxymethylcytosine
    		99.91%
    5-Hydroxymethylcytosine (5hmC) is an oxidized forms of 5-methylcytosine (5mC) in mammalian DNA. 5-Hydroxymethylcytosine is produced from 5mC in an enzymatic pathway involving three 5mC oxidases, Ten-eleven translocation (TET)1, TET2, and TET3. The conversion of 5mC into 5hmC can be the first step in a pathway leading towards DNA demethylation. 5-Hydroxymethylcytosine is associated with gene transcription and frequently used as a mark to investigate dynamic DNA methylation conversion during mammalian development.
    5-Hydroxymethylcytosine
  • HY-N0349S1
    Methyl Paraben-13C6
    		99.90%
    Methyl Paraben-13C6 (Methyl 4-hydroxybenzoate-13C6) is a 13C labeled Methyl Paraben (HY-N0349). Methyl Paraben, isolated from the barks of Tsuga dumosa the methyl ester of p-hydroxybenzoic acid, is a standardized chemical allergen. Methyl Paraben is a stable, non-volatile compound used as an antimicrobial preservative in foods, agents and cosmetics. The physiologic effect of Methyl Paraben is by means of increased histamine release, and cell-mediated immunity.
    Methyl Paraben-<sup>13</sup>C<sub>6</sub>
  • HY-113301S2
    Hexacosanoic acid-d3
    Hexacosanoic acid-d3 is deuterium labeled Hexacosanoic acid. Hexacosanoic acid is a long-chain fatty acid related to various diseases such as adrenoleukodystrophy (ALD), adrenomyeloneuropathy (AMN) and atherosclerosis.
    Hexacosanoic acid-d<sub>3</sub>
  • HY-N1480R
    (-)-Fucose (Standard)
    (-)-Fucose (Standard) is the analytical standard of (-)-Fucose. This product is intended for research and analytical applications. (-)-Fucose is classified as a member of the hexoses, plays a role in A and B blood group antigen substructure determination, selectin-mediated leukocyte-endothelial adhesion, and host-microbe interactions. (-)-Fucose is orally active, inhibits CL11-induced inflammatory response in kidney and tumor growth.
    (-)-Fucose (Standard)
  • HY-B0215S
    Acetylcysteine-d3
    Acetylcysteine-d3 is the deuterium labeled Acetylcysteine. Acetylcysteine (N-Acetylcysteine) is a mucolytic agent which reduces the thickness of the mucus. Acetylcysteine is a ROS inhibitor. Acetylcysteine is a cysteine precursor, prevents hemin-induced ferroptosis by neutralizing toxic lipids generated by arachidonate-dependent activity of 5-lipoxygenases. Acetylcysteine induces cell apoptosis. Acetylcysteine also has anti-influenza virus activities. In addition, Acetylcysteine is the most stable form of cysteine during drug delivery and can be used in disulfidptosis studies.
    Acetylcysteine-d<sub>3</sub>
  • HY-128374R
    D-Glucose 6-phosphate (disodium salt) (Standard)
    D-Glucose 6-phosphate disodium salt (Standard) is the analytical standard of D-Glucose 6-phosphate disodium salt (HY-128374). This product is intended for research and analytical applications. D-Glucose-6-phosphate disodium salt is a glucose sugar phosphorylated at the hydroxy group on carbon 6.
    D-Glucose 6-phosphate (disodium salt) (Standard)
  • HY-113118
    AAMU
    		99.34%
    AAMU (5-Acetylamino-6-amino-3-methyluracil) is the main metabolite of caffeine in the human body.
    AAMU
  • HY-W017443S2
    L-Asparagine-13C4,15N2,d3 monohydrate
    		99.90%
    L-Asparagine-13C4,15N2,d3 (monohydrate) is the deuterium, 13C-, and 15-labeled L-Asparagine monohydrate. L-Asparagine monohydrate ((-)-Asparagine monohydrate) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.
    L-Asparagine-<sup>13</sup>C<sub>4</sub>,<sup>15</sup>N<sub>2</sub>,d<sub>3</sub> monohydrate
  • HY-W004515
    3-Pyridylacetic acid hydrochloride
    		99.72%
    3-Pyridineacetic acid hydrochloride is a higher homologue of nicotinic acid, a breakdown product of nicotine (and other tobacco alkaloids).
    3-Pyridylacetic acid hydrochloride
  • HY-15129R
    O-Phospho-L-serine (Standard)
    O-Phospho-L-serine (Standard) (L-Serine O-phosphate (Standard)) is the analytical standard of O-Phospho-L-serine (HY-15129). This product is intended for research and analytical applications. O-Phospho-L-serine is the immediate precursor to L-cystein in the serine synthesis pathway, and an agonist at the group III mGluR receptors (mGluR4, mGluR6, mGluR7, and mGluR8). O-Phospho-L-serine also acts as a weak antagonist for mGluR1 and a potent antagonist for mGluR2.
    O-Phospho-L-serine (Standard)
  • HY-W015061R
    Phenylacetylglycine (Standard)
    Phenylacetylglycine (Standard) is the analytical standard of Phenylacetylglycine. This product is intended for research and analytical applications. Phenylacetylglycine is a gut microbial metabolite that can activate β2AR. Phenylacetylglycine protects against cardiac injury caused by ischemia/reperfusion.
    Phenylacetylglycine (Standard)
  • HY-101410R
    SDMA (Standard)
    SDMA (Standard) is the analytical standard of SDMA. This product is intended for research and analytical applications. SDMA (Symmetric dimethylarginine) is an endogenous inhibitor of nitric oxide (NO) synthase activity. SDMA, a novel kidney biomarker, permits earlier diagnosis of kidney disease than traditional creatinine testing.
    SDMA (Standard)
  • HY-164690A
    Nicotinamide-guanine dinucleotide sodium
    Nicotinamide-guanine dinucleotide sodium, a NAD sodium (HY-B0445A) analog, is an oxidized forms of nicotinamide guanine dinucleotide. Nicotinamide-guanine dinucleotide sodium serves as coenzymes for alcohol dehydrogenase (ADH) in vitro.
    Nicotinamide-guanine dinucleotide sodium
Cat. No. Product Name / Synonyms Application Reactivity