2. Metabolic Enzyme/Protease Others
  3. Endogenous Metabolite Isotope-Labeled Compounds
  4. 3-Hydroxyanthranilic acid-d3

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3-Hydroxyanthranilic acid-d<sub>3</sub> Chemical Structure

3-Hydroxyanthranilic acid-d3 Chemical Structure

CAS No. : 1794970-56-1

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Other Forms of 3-Hydroxyanthranilic acid-d3:

3-Hydroxyanthranilic acid-d3 Related Antibodies

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Description
In Vitro

Stable or radioisotope-labeled compounds allow precise tracking and quantification of individual atoms in metabolic pathways. Stable isotopes generally do not change molecular properties but may slightly affect metabolic kinetics; radioactive isotopes may interfere with cells. Markers can distinguish endogenous and exogenous metabolites, reduce false positives, and are beneficial to quantification and reconstruction of metabolic pathways[2].
In cell culture or enzymatic reactions, the use of isotope markers can precisely control the concentration and exposure time, making it easy to study metabolic reactions and enzyme activities. Through stable isotope analytical metabolomics (SIRM), cellular metabolic networks can be studied, key metabolic nodes and regulatory mechanisms can be identified, and targets can be provided for compound development.
Isotope-labeled compounds can be used in competition binding experiments to evaluate the affinity and binding kinetics of compounds to receptors to help optimize design. Stable isotope labels are used as internal standards in mass spectrometry analysis to improve analysis accuracy and reproducibility and reduce matrix effect interference[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

3-Hydroxyanthranilic acid-d3 Related Antibodies
In Vivo

Isotopic labels can non-invasively track the distribution, transformation and clearance of compounds and their metabolites in the body through techniques such as mass spectrometry (MS) and nuclear magnetic resonance (NMR), which is beneficial to the study of pharmacometabolic kinetics (ADME).
Isotope labeling can reveal specific steps in metabolic pathways. Using compounds with stable isotope labels at specific locations directly in humans or animal models can also help verify drug mechanisms and evaluate unexpected side effects, improving the accuracy and efficiency of clinical research[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

156.15

Formula

C7H4D3NO3
CAS No.
Unlabeled CAS
Appearance

Solid

Color

Off-white to light brown

SMILES

OC(C1=C(C(O)=C([2H])C([2H])=C1[2H])N)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (320.20 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.4041 mL 32.0205 mL 64.0410 mL
5 mM 1.2808 mL 6.4041 mL 12.8082 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.28%

SDS (393 KB)

COA (251 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 6.4041 mL 32.0205 mL 64.0410 mL 160.1025 mL
5 mM 1.2808 mL 6.4041 mL 12.8082 mL 32.0205 mL
10 mM 0.6404 mL 3.2020 mL 6.4041 mL 16.0102 mL
15 mM 0.4269 mL 2.1347 mL 4.2694 mL 10.6735 mL
20 mM 0.3202 mL 1.6010 mL 3.2020 mL 8.0051 mL
25 mM 0.2562 mL 1.2808 mL 2.5616 mL 6.4041 mL
30 mM 0.2135 mL 1.0673 mL 2.1347 mL 5.3367 mL
40 mM 0.1601 mL 0.8005 mL 1.6010 mL 4.0026 mL
50 mM 0.1281 mL 0.6404 mL 1.2808 mL 3.2020 mL
60 mM 0.1067 mL 0.5337 mL 1.0673 mL 2.6684 mL
80 mM 0.0801 mL 0.4003 mL 0.8005 mL 2.0013 mL
100 mM 0.0640 mL 0.3202 mL 0.6404 mL 1.6010 mL
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3-Hydroxyanthranilic acid-d3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

3-Hydroxyanthranilic acid-d31794970-56-1Endogenous MetaboliteIsotope-Labeled CompoundsInhibitorinhibitorinhibit

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