2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-100587R
    D-Glutamine (Standard)
    D-Glutamine (Standard)
  • HY-E70247
    (S)-3-Hydroxyhexanoyl-CoA
    (S)-3-Hydroxyhexanoyl-CoA (L-3-Hydroxyhexanoyl-CoA) is a hydroxy fatty acyl-CoA.
    (S)-3-Hydroxyhexanoyl-CoA
  • HY-113215S
    Allotetrahydrocortisol-d5
    Allotetrahydrocortisol-d5 is the deuterium labeled Allotetrahydrocortisol. Allotetrahydrocortisol (5a-Tetrahydrocortisol) is a metabolite of Cortisol. Cortisol is the main glucocorticoid in human. It is produced in adrenal cortex and plays a crucial role in many physiological processes[1][2].
    Allotetrahydrocortisol-d<sub>5</sub>
  • HY-113252R
    2-Methoxyestrone (Standard)
    Alitame (hydrate) (Standard) is the analytical standard of Alitame (hydrate). This product is intended for research and analytical applications. Alitame (hydrate) is a high-intensity sweetener formed from the amino acids L-aspartic acid and D-alanine, and an amine derived from thietane.
    2-Methoxyestrone (Standard)
  • HY-P3016B
    Aspartate aminotransferase, Human liver
    Aspartate aminotransferase (GOT), Human liver is an aminotransferase derived from human liver and is commonly used in biochemical research. Aspartate aminotransferase, Human liver catalyzes the conversion of aspartate and alpha-ketoglutarate to oxaloacetate and glutamate.
    Aspartate aminotransferase, Human liver
  • HY-W009162S1
    Cytidine 5′-monophosphate-13C9 dilithium
    Cytidine 5′-monophosphate-13C9 (5'-Cytidylic acid-13C9 dilithium; 5'-CMP-13C9) dilithium is 13C-labeled Cytidine 5'-monophosphate (HY-W009162). Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide which is used as a monomer in RNA. Cytidine 5'-monophosphate consists of the nucleobase cytosine, the pentose sugar ribose, and the phosphate group.
    Cytidine 5′-monophosphate-<sup>13</sup>C<sub>9</sub> dilithium
  • HY-124550
    Sarcophine
    Sarcophine ((+)-Sarcophine) is a potent glycine receptor (GlyR) inhibitor with an IC50 value of 3.9 μM. Sarcophine is a nature product that could be isolated form the Red Sea soft coral Sarcophyton glaucum.
    Sarcophine
  • HY-N0111S2
    Coenzyme Q10-d9
    		98.23%
    Coenzyme Q10-d9 is the deuterium labeled Coenzyme Q10. Coenzyme Q10 is an essential cofactor of the electron transport chain and a potent antioxidant agent.
    Coenzyme Q10-d<sub>9</sub>
  • HY-107542R
    Oleoylethanolamide (Standard)
    Oleoylethanolamide (Standard)
  • HY-B0389S13
    D-Glucose-13C-3
    D-Glucose-13C-3 is the 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].
    D-Glucose-<sup>13</sup>C-3
  • HY-N0324B
    Cholic acid sodium hydrate
    Cholic acid sodium hydrate is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. Cholic acid sodium hydrate facilitates fat absorption and cholesterol excretion. Cholic acid sodium hydrate is orally active.
    Cholic acid sodium hydrate
  • HY-131897S
    1-Stearoyl-2-Arachidonoyl-d8-sn-Glycerol
    1-Stearoyl-2-Arachidonoyl-d8-sn-Glycerol is the deuterium labeled 1-Stearoyl-2-arachidonoyl-sn-glycerol. 1-Stearoyl-2-arachidonoyl-sn-glycerol is a diacylglycerol (DAG) containing polyunsaturated fatty acids. 1-Stearoyl-2-arachidonoyl-sn-glycerol can activate PKC. 1-Stearoyl-2-arachidonoyl-sn-glycerol also can augment nonselective cation channel (NSCC) activity[1][2].
    1-Stearoyl-2-Arachidonoyl-d<sub>8</sub>-sn-Glycerol
  • HY-76547S
    p-Toluic acid-d4
    p-Toluic acid-d4 is the deuterium labeled p-Toluic acid[1]. p-Toluic acid (4-Methylbenzoic acid) is a substituted benzoic acid and can be used as an intermediate for the synthesis of para-aminomethylbenzoic acid (PAMBA), p-tolunitrile, etc.
    p-Toluic acid-d<sub>4</sub>
  • HY-P2879A
    Cholesterol esterase, Porcine pancreas
    Cholesterol esterase, Porcine pancreas is an enzyme that hydrolyzes cholesterol ester to cholesterol and free fatty acid in the intestinal lumen. Cholesterol synthesized in the acinar cells and is stored in zymogen granules. Cholesterol esterase is also known as bile salt-stimulated lipase and carboxy ester lipasea, acts function for acceleration of cholesterol absorption.
    Cholesterol esterase, Porcine pancreas
  • HY-B0389S4
    D-Glucose-d1-2
    D-Glucose-d1-2 is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].
    D-Glucose-d<sub>1</sub>-2
  • HY-N0537S5
    Xylose-3-13C
    Xylose-3-13C is the 13C labeled Xylose.
    Xylose-3-<sup>13</sup>C
  • HY-N0680R
    Thiamine (hydrochloride) (Standard)
    Thiamine (hydrochloride) (Standard) is the analytical standard of Thiamine (hydrochloride). This product is intended for research and analytical applications. Thiamine hydrochloride (Thiamine chloride hydrochloride) is an essential micronutrient needed as a cofactor for many central metabolic enzymes.
    Thiamine (hydrochloride) (Standard)
  • HY-113121S1
    Vanillylmandelic acid-d
    Vanillylmandelic acid-d is the deuterium labeled Vanillylmandelic acid. Vanillylmandelic acid is the endproduct of epinephrine and norepinephrine metabolism. Vanillylmandelic acid can be used as an indication of the disorder in neurotransmitter metabolism as well. Vanillylmandelic acid has antioxidant activity towards DPPH radical with an IC50 value of 33 μM[1].
    Vanillylmandelic acid-d
  • HY-N0486S11
    L-Leucine-d
    L-Leucine-d is the deuterium labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1].
    L-Leucine-d
  • HY-N1429S2
    Taurochenodeoxycholic acid-d4-1 sodium
    Taurochenodeoxycholic acid-d4-1 (sodium) is the deuterium labeled Taurochenodeoxycholic acid. Taurochenodeoxycholic acid (12-Deoxycholyltaurine) sodium is one of the main bioactive substances of animals' bile acid. Taurochenodeoxycholic acid sodium induces apoptosis and shows obvious anti-inflammatory and immune regulation properties[1][2].
    Taurochenodeoxycholic acid-d<sub>4</sub>-1 sodium
Cat. No. Product Name / Synonyms Application Reactivity