2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-Y1422C
    Lipase, Chromobacterium viscosum
    Lipase, Chromobacterium viscosum catalyzes the hydrolysis of ester bonds in lipids into glycerol and fatty acids. Lipase, Chromobacterium viscosum is involved in the digestion of fats and can be used industrially for the production of flavors, pharmaceuticals, and biodiesel.
    Lipase, Chromobacterium viscosum
  • HY-N11287
    UDP-xylose
    UDP-xylose is a natural product that could be isolated from Cryptococcus laurentii (NRRL Y-1401). UDP-xylose is a sugar donor for the synthesis of glycoproteins, polysaccharides, various metabolites, and oligosaccharides in plants, vertebrates, and fungi.
    UDP-xylose
  • HY-16622B
    GSK 1842799 hydrochloride
    GSK 1842799 hydrochloride is a selective S1P1 receptor agonist with potent agonist activity and exceptional selectivity over S1P3. GSK 1842799 hydrochloride demonstrates good oral bioavailability and rapid conversion to its active phosphorylated form. GSK 1842799 hydrochloride significantly reduces blood lymphocyte counts in vivo following oral administration. GSK 1842799 hydrochloride has shown efficacy comparable to FTY720 in the mouse EAE model of multiple sclerosis.
    GSK 1842799 hydrochloride
  • HY-133186R
    Fenamidone (Standard)
    Fenamidone (Standard) is the analytical standard of Fenamidone. This product is intended for research and analytical applications. Fenamidone is the active compound.
    Fenamidone (Standard)
  • HY-11084
    SNAP-7941
    SNAP-7941 is a selective antagonist with anxiolytic, antidepressant and appetite suppressant activities. SNAP-7941 showed promising biological activity in initial animal studies. SNAP-7941 targets the melanin concentrating hormone receptor MCH1 and has significant inhibitory potential. SNAP-7941 was shown to inhibit the centrally induced MCH-induced drinking effect in in vivo studies.
    SNAP-7941
  • HY-N10293
    Monaschromone
    Monaschromone, a polyketide metabolite, significantly inhibits the growth of B. cinerea, A. solani, M. oryzae, and G. saubinettii, with the MIC values ranging from 6.25 to 12.5 μM.
    Monaschromone
  • HY-124489S
    2-Hydroxyestradiol-13C6
    2-Hydroxyestradiol-13C6 is the 13C-labeled 2-Hydroxyestradiol. 2-Hydroxyestradiol, a metabolite of 17β-estradiol with minimal estrogenic activity, possesses antioxidant effects and reacts with DNA to form stable adducts and exerts genotoxicity[1][3].
    2-Hydroxyestradiol-<sup>13</sup>C<sub>6</sub>
  • HY-W019704R
    N-Acetyl-DL-methionine (Standard)
    N-Acetyl-DL-methionine (Standard) is the analytical standard of N-Acetyl-DL-methionine. This product is intended for research and analytical applications. N-Acetyl-DL-methionine is an endogenous metabolite.
    N-Acetyl-DL-methionine (Standard)
  • HY-N0131R
    Stigmasterol (Standard)
    Stigmasterol (Standard) is the analytical standard of Stigmasterol (HY-N0131). This product is intended for research and analytical applications. Stigmasterol is a plant sterol which has been focused on the cholesterol-lowering activity and is valued as an anti-stiffness factor in the therapy of rheumatic diseases.
    Stigmasterol (Standard)
  • HY-113400
    Cytidine 5'-diphosphate
    Cytidine 5'-diphosphate (Cytidine diphosphate) is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis.
    Cytidine 5'-diphosphate
  • HY-113167
    2-Phosphoglyceric acid
    2-Phosphoglyceric acid (DL-2-phosphoglyceric acid) is a glycolysis substrate. It is catalyzed by enolase into phosphoenolpyruvate (PEP).
    2-Phosphoglyceric acid
  • HY-N7387R
    3-​Oxocholic acid (Standard)
    Butylphthalide (Standard) is the analytical standard of Butylphthalide. This product is intended for research and analytical applications. Butylphthalide (3-n-Butylphthalide) is an active molecule against cerebral ischemia. It was originally isolated from celery species and has been shown to be effective in stroke animal models.
    3-​Oxocholic acid (Standard)
  • HY-W013075R
    Rutin (trihydrate) (Standard)
    Rutin (trihydrate) (Standard) is the analytical standard of Rutin (trihydrate). This product is intended for research and analytical applications. Rutin (Rutoside) trihydrate is a multifunctional natural flavonoid glycoside. Rutin trihydrate has been demonstrating excellent antioxidant, anti-inflammatory, anti-diabetic, and anti-carcinogenic properties. Cardioprotective and neuroprotective activities .
    Rutin (trihydrate) (Standard)
  • HY-W414498
    1-Deoxysphingosine
    1-Deoxysphingosine is elevated in lymphoblasts of individuals with hereditary sensory neuropathy type 1 (HSAN1) disorder; it features a (4E) double bond in its structure and is produced through the catabolism of 1-deoxyceramide catalyzed by the ceramidase enzyme, classifying it as an unsaturated deoxy-sphingoid base.
    1-Deoxysphingosine
  • HY-117526
    (-)-Mesembrine
    (-)-Mesembrine, a psychoactive alkaloid, is a partial racemate in S. strictum and S. tortuosum in smaller amounts.
    (-)-Mesembrine
  • HY-N7117R
    1,4-Cineole (Standard)
    1,4-Cineole (Standard) is the analytical standard of 1,4-Cineole. This product is intended for research and analytical applications. 1,4-Cineole is a widely distributed, natural, oxygenated monoterpene. 1,4-Cineole, present in Rhododendron anthopogonoides, activates both human TRPM8 and human TRPA1.
    1,4-Cineole (Standard)
  • HY-19459
    Ocaphane
    Ocaphane (AT-581) is a potent antitumor agent used in the study of various animal tumors.
    Ocaphane
  • HY-B0400S2
    D-Sorbitol-13C-1
    D-Sorbitol-13C-1 is the 13C labeled D-Sorbitol. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and dietary
    D-Sorbitol-<sup>13</sup>C-1
  • HY-N5134S1
    5'-Guanylic acid-13C10 dilithium
    5'-Guanylic acid-13C10 (5'-GMP-13C10 dilithium; 5'-guanosine monophosphate-13C10) dilithium is 13C-labeled 5'-Guanylic acid (HY-N5134). 5'-Guanylic acid (5'-GMP) is involved in several metabolic disorders, including the AICA-ribosiduria pathway, adenosine deaminase deficiency, adenine phosphoribosyltransferase deficiency (aprt), and the 2-hydroxyglutric aciduria pathway.
    5'-Guanylic acid-<sup>13</sup>C<sub>10</sub> dilithium
  • HY-75087S
    (R)-Pyrrolidine-2-carboxylic acid-d3
    (R)-Pyrrolidine-2-carboxylic acid-d3 is the deuterium labeled (R)-pyrrolidine-2-carboxylic acid. (R)-pyrrolidine-2-carboxylic acid is an endogenous metabolite.
    (R)-Pyrrolidine-2-carboxylic acid-d<sub>3</sub>
Cat. No. Product Name / Synonyms Application Reactivity