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  4. GSK 1842799 hydrochloride

GSK 1842799 hydrochloride is a selective S1P1 receptor agonist with potent agonist activity and exceptional selectivity over S1P3. GSK 1842799 hydrochloride demonstrates good oral bioavailability and rapid conversion to its active phosphorylated form. GSK 1842799 hydrochloride significantly reduces blood lymphocyte counts in vivo following oral administration. GSK 1842799 hydrochloride has shown efficacy comparable to FTY720 in the mouse EAE model of multiple sclerosis.

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GSK 1842799 hydrochloride Chemical Structure

GSK 1842799 hydrochloride Chemical Structure

CAS No. : 1277165-15-7

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GSK 1842799 hydrochloride Related Antibodies

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Description

GSK 1842799 hydrochloride is a selective S1P1 receptor agonist with potent agonist activity and exceptional selectivity over S1P3. GSK 1842799 hydrochloride demonstrates good oral bioavailability and rapid conversion to its active phosphorylated form. GSK 1842799 hydrochloride significantly reduces blood lymphocyte counts in vivo following oral administration. GSK 1842799 hydrochloride has shown efficacy comparable to FTY720 in the mouse EAE model of multiple sclerosis.

Molecular Weight

504.44

Formula

C20H30Cl2F3N3O2S
CAS No.
SMILES

OC[C@](N)(C1=NN=C(C2=CC(C(F)(F)F)=C(C=C2)OCCCCCCCC)S1)C.Cl.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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GSK 1842799 hydrochloride Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GSK 18427991277165-15-7GSK1842799GSK-1842799OthersInhibitorinhibitorinhibit

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HY-16622B
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