2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B0141AS1
    Alpha-Estradiol-d2
    		≥99.0%
    Alpha-Estradiol-d2 is the deuterium labeled Alpha-Estradiol. Alpha-Estradiol is a weak estrogen and a 5α-reductase inhibitor which is used as a topical medication in the treatment of androgenic alopecia[1].
    Alpha-Estradiol-d<sub>2</sub>
  • HY-W010104AR
    Methionine sulfoxide (Standard)
    Methionine sulfoxide (Standard)
  • HY-B0456S1
    Riboflavin-5-Phosphate-13C4,15N2-1
    Riboflavin-5-Phosphate-13C4,15N2-1 is the 13C-labeled and 15N-labeled Riboflavin. Riboflavin is an easily absorbed micronutrient with a key role in maintaining health in humans and other animals.
    Riboflavin-5-Phosphate-<sup>13</sup>C<sub>4</sub>,<sup>15</sup>N<sub>2</sub>-1
  • HY-136494
    Fluprostenol
    Fluprostenol (ICI 81008) is a synthetic prostaglandin F2α (PGF2α) derivative. Fluprostenol, as a luteolytic agent, can cause luteal degeneration and regulate reproductive cycle. Fluprostenol can be used in the study of infertility in animals and the control of the reproductive cycle of domestic animals.
    Fluprostenol
  • HY-123405
    YM-75440
    YM-75440 is an orally active inhibitor of squalene synthase.
    YM-75440
  • HY-90006S2
    5-Fluorouracil-15N2
    		≥99.0%
    5-Fluorouracil-15N2 is the 15N-labeled 5-Fluorouracil. 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer[1][2]. 5-Fluorouracil also inhibits HIV[3].
    5-Fluorouracil-<sup>15</sup>N<sub>2</sub>
  • HY-Y1139R
    Pimelic acid (Standard)
    Pimelic acid (Standard) is the analytical standard of Pimelic acid. This product is intended for research and analytical applications. Pimelic acid is the organic compound and its derivatives are involved in the biosynthesis of the amino acid called lysine.Pimelic acid can be used in keratoconus research.
    Pimelic acid (Standard)
  • HY-N12530
    16,17-EDT
    16,17-EDT is an oxylipin and a metabolite of adrenic acid formed by the cytochrome P450 (CYP) pathway.
    16,17-EDT
  • HY-126199R
    Tetrachlorvinphos (Standard)
    Tetrachlorvinphos (Standard) is the analytical standard of Tetrachlorvinphos. This product is intended for research and analytical applications. Tetrachlorvinphos is an organophosphorus pesticide that has the activity of inhibiting cholinesterase. Tetrachlorvinphos is used as a pesticide, mainly for the control of pests. Tetrachlorvinphos has low toxicity to mammals.
    Tetrachlorvinphos (Standard)
  • HY-W004515S
    3-Pyridylacetic acid-d4 hydrochloride
    3-Pyridylacetic acid-d4 (hydrochloride) is the deuterium labeled 3-Pyridylacetic acid hydrochloride[1]. 3-Pyridineacetic acid hydrochloride is a higher homologue of nicotinic acid, a breakdown product of nicotine (and other tobacco alkaloids)[2][3].
    3-Pyridylacetic acid-d<sub>4</sub> hydrochloride
  • HY-130392
    Wofapyrin
    Wofapyrin (Rheumopyrin) is an antipyretic and anti-inflammatory agent, exhibiting notable activity in promoting lesion volume compared to penicillin, while being less effective than OTESOLUT and nearly equivalent to 5% WOFAPYRIN.
    Wofapyrin
  • HY-116472
    alpha-RA-F
    alpha-RA-F (α-RA-F) is a compound that can promote collagen synthesis and has the activity of reducing the expression level of matrix metalloproteinases (MMPs). alpha-RA-F enhances collagen synthesis in human fibroblasts without causing cytotoxicity. alpha-RA-F has demonstrated its important potential in the pharmaceutical, pharmaceutical and cosmetic industries by regulating collagen synthesis and MMPs expression levels.
    alpha-RA-F
  • HY-18732B
    L-NMMA citrate
    L-NMMA citrate competitively antagonizes L-arginine, and thus inhibits production of nitric oxide (NO). L-NMMA is utilized as NO synthase antagonist in experimental settings.
    L-NMMA citrate
  • HY-127151
    R-(-)-Phencynonate hydrochloride
    Levophencynonate is a muscarinic receptor antagonist with anticholinergic activity. The biological activity of levophencynonate makes it a key target for the determination of its concentration in human plasma in medical research. Levophencynonate was analyzed by high performance liquid chromatography tandem mass spectrometry (HPLC-MS/MS) and showed good specificity and linearity.
    R-(-)-Phencynonate hydrochloride
  • HY-B1804S1
    Tricaprilin-d50
    Tricaprilin-d50 (Trioctanoin-d50
    Tricaprilin-d<sub>50</sub>
  • HY-W006057AR
    Sodium 3-methyl-2-oxobutanoate (Standard)
    Sodium 3-methyl-2-oxobutanoate (Standard)
  • HY-N0086S3
    N6-Methyladenosine-13C3
    N6-Methyladenosine-13C3 (6-Methyladenosine-13C3) is 13C-labeled N6-Methyladenosine (HY-N0086). N6-Methyladenosine is the most prevalent internal (non-cap) modification present in the messenger RNA (mRNA) of all higher eukaryotes. N6-Methyladenosine can modifies viral RNAs and has antiviral activities.
    N6-Methyladenosine-<sup>13</sup>C<sub>3</sub>
  • HY-125060
    Viridicatin
    Viridicatin is a fungal metabolite from Penicillium species. Viridicatin shows slight in vitro antibiotic activity against Mycobacterium tuberculosis.
    Viridicatin
  • HY-E70406
    Cholesterol Dehydrogenase, Nocardia sp.
    Cholesterol Dehydrogenase, Nocardia sp. is an enzyme that uses nicotinamide adenine dinucleotide/nicotinamide adenine dinucleotide phosphate (NAD(P)) as its cofactor in oxidizing cholesterol to form cholest-4-en-3-one. This enzyme oxidizes the hydroxyl group at the 3 position of the sterol ring to form a ketone.
    Cholesterol Dehydrogenase, Nocardia sp.
  • HY-Y1809S
    1-Hydroxyoctadecane-d37
    1-Hydroxyoctadecane-d37 is the deuterium labeled 1-Hydroxyoctadecane[1]. 1-Hydroxyoctadecane is an endogenous metabolite.
    1-Hydroxyoctadecane-d<sub>37</sub>
Cat. No. Product Name / Synonyms Application Reactivity