Others Agonist

Others Agonists (57):

Cat. No.	Product Name	Effect	Purity

HY-P99055

Urelumab	Agonist	99.138%
Urelumab, a fully human, non-ligand binding, CD137 agonist IgG4 monoclonal antibody, enhances T-cell and natural killer-cell antitumor activity, and may enhance cytotoxic activity of Rituximab (HY-P9913). Urelumab can be used for the research of diffuse large B-cell lymphoma (DLBCL), follicular lymphoma (FL), and other types of non-Hodgkin lymphoma (NHL).

HY-149164

BTB09089	Agonist	99.43%
BTB09089 is a T cell death-associated gene 8 (TDAG8/GPR65) specific agonist. BTB09089 increases TDAG8 expression and regulates the cytokine production of T cells and macrophages.

HY-P0267

Melanotan (MT)-II	Agonist	99.82%
Melanotan (MT)-II, a synthetic melanocortin receptor agonist, is an injectable peptide hormone used to promote tanning.

HY-P0168

Cibinetide	Agonist	99.68%
Cibinetide (ARA290) is an EPO-derivative, acting as a specific agonist of erythropoietin/CD131 heteroreceptor, and used for neurological disease treatment.

HY-P2198

PAMP-12(human, porcine)	Agonist
PAMP-12(human, porcine) is a major component of immunoreactive (ir)-PAMP, is processed from the adrenomedullin precursor, is a potent hypotensive peptide and participates in cardiovascular control.

HY-W016868

3-Chloro-5-hydroxybenzoic acid	Agonist	98.01%
3-Chloro-5-hydroxybenzoic acid is a potent, orally active and selective lactate receptor GPR81 agonist, with an EC₅₀ of 16 μM for human GPR81. 3-Chloro-5-hydroxybenzoic acid exhibits favorable in vivo effects on lipolysis in a mouse model of obesity.

HY-P99046

Selicrelumab	Agonist
Selicrelumab is an agonist CD40 antibody, induces changes in the tumor microenvironment. Selicrelumab can be used for the research of pancreatic cance and neoadjuvant study.

HY-P0003

Nesiritide	Agonist	99.71%
Nesiritide (Brain Natriuretic Peptide-32 human) is an agonist of natriuretic peptide receptors (NPRs), with K_d values of 7.3 and 13 pM for NPR-A and NPR-C, respectively.

HY-P1211

Adrenocorticotropic Hormone (ACTH) (1-39), human	Agonist	99.09%
Adrenocorticotropic Hormone (ACTH) (1-39), human is a melanocortin receptor agonist.

HY-110329

ML179	Agonist	99.83%
ML179 (SR-1309) is a inverse LRH1 (Liver receptor homologue-1) agonist with IC₅₀ of 320 nM. ML179 shows anti-proliferation activity in MDA-MB-231 cells. ML179 has the potential for the research of ER-negative breast cancer.

HY-P5411

OVA-T4 Peptide	Agonist	99.59%
OVA-T4 Peptide (SIITFEKL, OVA (257-264) Variant) is a biological active peptide. (T4 peptide (SIITFEKL) is a variant of the agonist ovalbumin (OVA) peptide (257-264), SIINFEKL. OVA Peptide is a class I (Kb)-restricted peptide epitope of ovalbumin presented by the class I MHC (major histocompatibility complex) molecule, H-2Kb (class I genes of the mouse MHC).)

HY-155318A

GPR3 agonist-2	Agonist	98.80%
GPR3 agonist-2(compound 32) is a potent full agonist of G protein-coupled receptor 3, with the IC₅₀of 260 nM.

HY-153265

TAS2R14 agonist-2	Agonist	99.91%
TAS2R14 agonist-2 (compound 28.1) is a potent and selective TAS2R14 inhibitor with an EC₅₀ value of 72 nM.

HY-P1238A

Neuromedin U, rat TFA	Agonist	99.69%
Neuromedin U, rat TFA is a 23-amino acid brain-gut peptide. Neuromedin U (NMU), through its cognate receptor NMUR2 in the central nervous system, regulates several important physiological functions, including energy balance, stress response, and nociception.

HY-P1389

Neuropeptide S (human)	Agonist	99.71%
Neuropeptide S human, a neuropeptide, is a potent cognate neuropeptide S receptor (NPSR) agonist. Neuropeptide S human can be used for Alzheimer's disease (AD) research.

HY-P10365

VPM-p15	Agonist	98.18%
Vmm-p15 is a peptide agonist optimized for the adhesion G protein-coupled receptor GPR64 (also known as ADGRG2 or HE6). The affinity of VPM-p15 with GPR64 is significantly higher than that of the original p15 peptide. The cAMP level induced by VMM-P15 increased significantly, activated GPR64, and triggered downstream Gs, Gq, and G12/13 signaling. VPM-p15 can be used to study the activation mechanism of adherent GPCR family members.

HY-P2381

TRV120055	Agonist
TRV120055 is a G_q-biased agonists, exhibits 10-fold larger molecular efficacies at the AT₁R-Gq fusion protein compared with the AT₁R-βarr2 fusion protein.

HY-110291

A-971432	Agonist	≥99.0%
A-971432 is a potent, selective and orally active sphingosine-1-phosphate (S1P) receptor 5 agonist with IC₅₀s of .362, >10, 0.006 µM for S1P1, S1P3, S1P5 respectively. A-971432 protects blood–brain barrier (BBB) homeostasis. A-971432 reverses age-related cognitive decline. A-971432 has the potential for the research of alzheimer’s disease or multiple sclerosis .

HY-101459

RTC13	Agonist	99.31%
RTC13 restores dystrophin expression and improves muscle function in the mdx mouse model for Duchenne muscular dystrophy (DMD).

HY-P1035

Neuropeptide W-23 (human)	Agonist	99.84%
Neuropeptide W-23 (human) (NPW-23), the active form of Neuropeptide W, is an endogenous agonist of NPBW1 (GPR7) and NPBW2 (GPR8).

Name
Email *

	Sorry, but the email address you supplied was invalid.