2. Signaling Pathways
  3. Others
  4. Others
  5. Others Antagonist

Others Antagonist

Others Antagonists (29):

Cat. No. Product Name Effect Purity
  • HY-111444
    Auxinole
    		Antagonist 99.77%
    Auxinole is a potent auxin antagonist of TIR1/AFB receptors, binding TIR1 to block the formation of the TIR1-IAA-Aux/IAA complex and so inhibits auxin-responsive gene expression.
  • HY-112730
    PEO-IAA
    		Antagonist 99.70%
    PEO-IAA is an indole-3-acetic acid (IAA) antagonist. PEO-IAA is an auxin antagonist that binds to transport inhibitor response 1/auxin signaling F-box proteins (TIR1/AFBs).
  • HY-B0079
    Sugammadex sodium
    		Antagonist ≥98.0%
    Sugammadex sodium is a synthetic γ-cyclodextrin derivative, and acts as a reversal agent for neuromuscular block. Sugammadex sodium shows nephroprotective effect in ischemia-reperfusion injury.
  • HY-101483
    Dihydromunduletone
    		Antagonist 99.96%
    Dihydromunduletone (DHM) is a rotenoid derivative and a selective, potent adhesion G protein-coupled receptor (aGPCR) (GPR56 and GPR114/ADGRG5) antagonist with an IC 50 of 20.9 μM for GPR56, but not inhibit GPR110 or class A GPCRs.
  • HY-12664
    AF64394
    		Antagonist 98.01%
    AF64394 is a GPR3 inverse agonist, with a pIC50 of 7.3.
  • HY-101527
    20-HEDE
    		Antagonist ≥98.0%
    20-HEDE (WIT 002) is an antagonist of 20-hydroxyeicosatetraenoic acid (20-HETE).
  • HY-150205
    Succinate/succinate receptor antagonist 1
    		Antagonist 99.46%
    Succinate/succinate receptor antagonist 1 (compound 7a) is a succinate/succinate receptor antagonist. Succinate/succinate receptor antagonist 1 blocks succinate signaling in gingival tissue. Succinate/succinate receptor antagonist 1 inhibits the activation of succinate receptor 1 (SucnRl) with an IC50 value of 20 μΜ. Succinate/succinate receptor antagonist 1 can be used for the research of periodontal disease.
  • HY-128775
    JHU395
    		Antagonist 99.88%
    JHU395 is an orally-bioavailable and a plasma stable lipophilic glutamine antagonists (GA) proagent. JHU395 delivers 6-diazo-5-oxo-L-norleucine (DON) to malignant peripheral nerve sheath tumor (MPNST) in vitro and in vivo, and has antitumor activity in MPNST.
  • HY-B1014
    Acenocoumarol
    		Antagonist 99.87%
    Acenocoumarol is an anticoagulant that functions as a Vitamin K antagonist.
  • HY-B0325
    Phenindione
    		Antagonist 98.21%
    Phenindione is an anticoagulant and can act as a vitamin K antagonist.
  • HY-A0145
    Phenprocoumon
    		Antagonist 98.02%
    Phenprocoumon is a coumarin derivative that acts as a long acting oral anticoagulant and an antagonist of vitamin K.
  • HY-112659
    Lin28-let-7 antagonist 1
    		Antagonist 99.68%
    Lin28-let-7 antagonist 1 (compound 1632) is a potent antagonist of Lin28/pre-let-7 interaction. Lin28-let-7 antagonist 1 inhibits Lin28A binding to pre-let-7a-2, with an IC50 of 8 μM. Lin28-let-7 antagonist 1 inhibits proliferation in human cancer cells.
  • HY-15702
    HJC0350
    		Antagonist 98.11%
    HJC0350 is a potent and specific EPAC2 antagonist with an IC50 of 0.3 µM.
  • HY-14854
    Tecarfarin
    		Antagonist 98.65%
    Tecarfarin (ATI-5923) is an orally active and non-competitive vitamin K epoxide reductase (VKOR) antagonist, and impairs the activation of the vitamin K-dependent clotting factors II, VII, IX and X. Tecarfarin has the antithrombotic activity .
  • HY-110166
    PD 90780
    		Antagonist ≥99.0%
    PD 90780 is a non peptide antagonist of nerve growth factor (NGF). PD 90780 interacts with NGF, prevents NGF binds with p75NTR. PD 90780 inhibits NGF-p75NTR interaction with IC50s of 23.1 and 1.8 µM in PC12 cells and PC12nnr5 cells, respectively .
  • HY-U00017
    Coumetarol
    		Antagonist 99.01%
    Coumetarol (Dicumoxane) is a vitamin K antagonist.
  • HY-114745
    MoTP
    		Antagonist 98.30%
    MoTP is a specific platelet activating factor receptor antagonist and can induce melanocyte ablation. MoTP can be used for the research of cancer.
  • HY-117541
    Glycyl-glutamine
    		Antagonist ≥98.0%
    Glycyl-glutamine (Glycyl-L-glutamine), as a enzymatic cleavage product of β-endorphin, is apparently an endogenous antagonist of beta-endorphin(1-31) in several systems. Glycyl-glutamine (Glycyl-L-glutamine) is an activate and stable glutamine-containing neuropeptide over glutamine (Gln).
  • HY-151392
    LPA5 antagonist 2
    		Antagonist 99.62%
    LPA5 antagonist 2 (compound 65) is a high aqueous solubility LPA5 (lysophosphatidic acid receptor 5) antagonist. LPA5 antagonist 2 significantly attenuates nociceptive hypersensitivity and it can be used for the research of inflammatory and neuropathic pains.
  • HY-118561
    Bermoprofen
    		Antagonist 99.91%
    Bermoprofen (AD-1590) is an orally active non-steroidal anti-inflammatory agent. Bermoprofen has potent antipyretic activities with a short biological half-life. Bermoprofen is a potent antagonist of LPS-induced fever in rabbits.