2. Signaling Pathways
  3. Others
  4. Others
  5. Others Degrader

Others Degrader

Others Degraders (2):

Cat. No. Product Name Effect Purity
  • HY-160438B
    PBX-7011 TFA
    		Degrader
    PBX-7011 TFA is a derivative of camptothecin (HY-16560), which inhibits expressions of the cancer related survival genes DDX5, Survivin, Mcl-1 and XIAP in cells FaDu, degrades DDX5 proteins and exhibits anticancer activity.
  • HY-162896
    And1 degrader 1
    		Degrader
    And1 degrader 1 (Compound A15) is a degrader of the acidic nucleoplasmic DNA-binding protein 1 (And1), which can significantly induce the degradation of And1 in NSCLC cells. And1 degrader 1 (5 μM) combined with Olaparib (HY-10162) (1 μM) effectively inhibits the proliferation of A549 and H460 cells. And1 degrader 1 can be used in cancer research.