2. Signaling Pathways
  3. Membrane Transporter/Ion Channel
  4. P-glycoprotein
  5. P-glycoprotein Substrate

P-glycoprotein Substrate

P-glycoprotein Substrates (2):

Cat. No. Product Name Effect Purity
  • HY-170569
    Cetagliptin
    		Substrate
    Cetagliptin is an orally active inhibitor for dipeptidyl peptidase 4 (DPP-4) and CYP2D6 (IC50 of 6 µM). Cetagliptin is a substrate for P-glycoprotein. Cetagliptin reduces the GLP-1 degradation, maintains the level of postprandial blood sugar, and can be used in type 2 diabetes mellitus research.
  • HY-129764
    Prostaglandin F3α
    		Substrate
    Prostaglandin F3α (PGF3α) is an eicosapentaenoic acid (EPA)-derived bioactive lipid mediator that has anti-cancer and anti-inflammatory effects. Prostaglandin F3α is a substrate of ABCC4 with a Km of 12.1 μM. Prostaglandin F3α can be used for the research of diabetes.