2. Signaling Pathways
  3. Membrane Transporter/Ion Channel
  4. P-glycoprotein
  5. P-glycoprotein Inducer

P-glycoprotein Inducer

P-glycoprotein Inducer (1):

Cat. No. Product Name Effect Purity
  • HY-N0217
    Benzoylaconine
    		Inducer 99.92%
    Benzoylaconine (Benzoylaconitine) is an orally active monoester alkaloid found in the traditional Chinese medicine Aconitum carmichaelii. Benzoylaconine is an ACE2 agonist (EC50: 1.5 μM) with antihypertensive and anti-heart failure effects. Benzoylaconine inhibits TLR-induced MAPK and NF-κB pathways to exert anti-inflammatory effects. Benzoylaconine upregulates the protein levels of P-gp, MRP2, and has anti-tumor effects.