2. Signaling Pathways
  3. Cell Cycle/DNA Damage
  4. PERK
  5. PERK Agonist

PERK Agonist

PERK Agonist (1):

Cat. No. Product Name Effect Purity
  • HY-114978
    VU0424465
    		Agonist
    VU0424465 is a potent and partial PAM (positive allosteric modulator)-agonist for mGlu5 mediated iCa2+ mobilization. VU0424465 exhibits high affinity at MPEP allosteric binding site, with a Ki value of 11.8 nM. VU0424465 is also a agonist for pERK1/2 in cortical neurons.