2. Signaling Pathways
  3. PROTAC
  4. PROTACs
  5. PROTACs Antagonist

PROTACs Antagonist

PROTACs Isoform Comparison

PROTACs Antagonists (2):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-143904
    PROTAC TTK degrader-1 2953426-43-0 98.01%
    PROTAC TTK degrader-1 is a potent TTK (threonine tyrosine kinase) PROTAC degrader, with DC50 values of 1.7 and 5.8 nM in COLO-205 and HCT-116 cell, respectively. PROTAC TTK degrader-1 exhibits target degradation and anticancer efficacy in a xenograft mouse model of COLO-205 human colorectal cancer cells.
    PROTAC TTK degrader-1
  • HY-143905
    PROTAC TTK degrader-2 2953426-48-5
    PROTAC TTK degrader-2 is a potent TTK (threonine tyrosine kinase) PROTAC degrader, with DC50 values of 3.1 and 12.4 nM in COLO-205 and HCT-116 cell, respectively. PROTAC TTK degrader-2 exhibits target degradation and anticancer efficacy in a xenograft mouse model of COLO-205 human colorectal cancer cells.
    PROTAC TTK degrader-2