2. Signaling Pathways
  3. Stem Cell/Wnt
  4. Smo
  5. Smo Activator

Smo Activator

Smo Activators (3):

Cat. No. Product Name Effect Purity
  • HY-15108
    Purmorphamine
    		Activator 99.89%
    Purmorphamine is a smoothened/Smo receptor agonist with an EC50 of 1 μM.
  • HY-12316
    20(S)-Hydroxycholesterol
    		Activator 98.70%
    20(S)-hydroxyCholesterol (20α-Hydroxycholesterol) is an allosteric activator of the oncoprotein smoothened (Smo) that activates the hedgehog (Hh) signaling pathway with an EC50 of 3 μM in a gene transcription reporter assay using NIH3T3 cells.
  • HY-12316R
    20(S)-Hydroxycholesterol (Standard)
    		Activator
    20(S)-Hydroxycholesterol (Standard) is the analytical standard of 20(S)-Hydroxycholesterol. This product is intended for research and analytical applications. 20(S)-hydroxyCholesterol (20α-Hydroxycholesterol) is an allosteric activator of the oncoprotein smoothened (Smo) that activates the hedgehog (Hh) signaling pathway with an EC50 of 3 μM in a gene transcription reporter assay using NIH3T3 cells.