2. Signaling Pathways
  3. Protein Tyrosine Kinase/RTK
  4. Src
  5. Lyn Isoform
  6. Lyn Inhibitor

Lyn Inhibitor

Lyn Inhibitor (1):

Cat. No. Product Name Effect Purity
  • HY-157442
    GLPG3312
    		Inhibitor 98.25%
    GLPG3312 (Compound 28) is an orally active SIK inhibitor with IC50 values of 2.0 nM, 0.7 nM and 0.6 nM for SIK1, SIK2 and SIK3, respectively. GLPG3312 exhibits anti-inflammatory and immunomodulatory activity in vitro on human primary myeloid cells and in vivo in mouse models. GLPG3312 has good oral bioavailability and can be used for research on inflammatory and immune diseases.