2. Signaling Pathways
  3. Apoptosis
  4. TNF Receptor
  5. TNFRSF1A/CD120a Isoform
  6. TNFRSF1A/CD120a Activator

TNFRSF1A/CD120a Activator

TNFRSF1A/CD120a Activators (3):

Cat. No. Product Name Effect Purity
  • HY-126360
    Oxazolone
    		Activator ≥98.0%
    Oxazolone is a haptenizing agent that induces acute or chronic inflammation of the large intestine and is used to construct models of colitis. Oxazolone can cause Th1/Th2-dependent colitis with weight loss and diarrhea. Oxazolone-induced inflammation can be mitigated by neutralizing anti-IL-4 or anti-TNF-α antibodies or decoy IL-13R2-α-FC proteins.
  • HY-145498
    HDMAPP triammonium
    		Activator
    HDMAPP triammonium is a potent phosphoantigen in the ammonium form and the pyrophosphate form of (E)-HDMAPP. HDMAPP is also a potent activator of γδ T cells and can induce T cell stimulation in vitro (EC50=0.39 nM, TNF-α).
  • HY-134950
    (E)-C-HDMAPP ammonium
    		Activator
    (E)-C-HDMAPP ammonium, is a potent phosphoantigen in ammonium form as well as a pyrophosphonate form of (E)-HDMAPP. (E)-C-HDMAPP is also an effective activator of γδ-T cells, induces T-cell stimulatory responses in vitro (EC50=0.91 nM for TNF-α release).