2. Signaling Pathways
  3. Apoptosis
  4. TNF Receptor
  5. TNFRSF5/CD40 Isoform
  6. TNFRSF5/CD40 Activator

TNFRSF5/CD40 Activator

TNFRSF5/CD40 Activator (1):

Cat. No. Product Name Effect Purity
  • HY-118250
    GSK2245035
    		Activator 99.85%
    GSK2245035 is a highly potent and selective intranasal Toll-Like receptor 7 (TLR7) agonist with preferential Type-1 interferon (IFN)-stimulating properties. GSK2245035 has pEC50s of 9.3 and 6.5 for IFNα and TFNα. GSK2245035 effectively suppresses allergen-induced Th2 cytokine production in human peripheral blood cell cultures. GSK2245035 is used for asthma.