2. Signaling Pathways
  3. Apoptosis
  4. ASK1
  5. ASK1 Inhibitor

ASK1 Inhibitor

ASK1 Inhibitor (1):

Cat. No. Product Name Effect Purity
  • HY-160851
    GDC-3280
    		Inhibitor 98.82%
    GDC-3280 (AK3287; AKEX0011) is an orally active compound based on Pirfenidone (HY-B0673)'s phenyl pyridone scaffold. GDC-3280 alleviates the inflammatory and fibrotic reaction of silicosis by inhibiting the ASK1-p38 MAPK pathway and regulating macrophage polarization. GDC-3280 exhibits anti-inflammatory and anti-fibrotic effects.