2. Signaling Pathways
  3. Immunology/Inflammation
  4. C-type Lectin-like Receptors (CTLRs)
  5. C-type Lectin-like Receptors (CTLRs) Inhibitor

C-type Lectin-like Receptors (CTLRs) Inhibitor

C-type Lectin-like Receptors (CTLRs) Inhibitors (5):

Cat. No. Product Name Effect Purity
  • HY-P9990
    Litifilimab
    		Inhibitor 99.42%
    Litifilimab is a humanized IgG1-κ antibody targeting to C-type lectin domain family 4 member C (CLEC4C). Litifilimab can be used for cutaneous lupus erythematosus (CLE) study.
  • HY-153489
    ISIS 329993
    		Inhibitor
    ISIS 329993 (ISIS-CRPRx) is an antisense oligonucleotide targeting to C-reactive protein (CRP). ISIS-CRPRx has been tested in a rodent model of rheumatoid arthritis (RA) and was shown to improve the clinical signs of arthritis
  • HY-155311
    NKG2D-IN-1
    		Inhibitor
    NKG2D-IN-1 (compound 21) is a natural killer group 2D receptor (NKG2D) inhibitor with IC50s of 0.3 µM and 0.7 µM in NKG2D/MICA and ULBP6 TR-FRET assays, respectively.
  • HY-153489A
    ISIS 329993 sodium
    		Inhibitor
    ISIS 329993 sodium is an antisense oligonucleotide targeting to C-reactive protein (CRP). ISIS-CRPRx sodium has been tested in a rodent model of rheumatoid arthritis (RA) and was shown to improve the clinical signs of arthritis
  • HY-W159303
    7-Hydroxy-2,2-dimethyl-4-chromanone
    		Inhibitor
    7-Hydroxy-2,2-dimethyl-4-chromanone (compound 41) is an inhibitor of DC-SIGN (Dendritic Cell-Specific Intercellular Adhesion Molecule 3 grabbing non-integrin), with an IC50 of 4.66 mM. DC-SIGN is the C-type lectin receptor presenting on the surface of both macrophages and dendritic cells.