2. Signaling Pathways
  3. Membrane Transporter/Ion Channel
  4. Ferroportin
  5. Ferroportin Inhibitor

Ferroportin Inhibitor

Ferroportin Inhibitors (8):

Cat. No. Product Name Effect Purity
  • HY-126302
    DMT1 blocker 2
    		Inhibitor 99.92%
    DMT1 blocker 2 is a direct inhibitor of divalent metal transporter 1 (DMT1), with an IC50 of 0.83 μM. DMT1 blocker 2 can block iron uptake by enterocytes in vivo.
  • HY-B2082
    Fursultiamine
    		Inhibitor 99.92%
    Fursultiamine is a vitamin B1 derivative, has anti-nociceptive and antineoplastic activity. Fursultiamine can be used for vitamin B1?deficiency, osteoarthritis (OA) and cancer research.
  • HY-B2082R
    Fursultiamine (Standard)
    		Inhibitor
  • HY-124703
    Pyrimidinone 8
    		Inhibitor
    Pyrimidinone 8 is a reversible linear non-competitive inhibitor of divalent metal transporter 1 (DMT1), with a Ki of 20 μM (hDMT1). Pyrimidinone 8 does not affect hDMT1 cell surface expression and shows no dependence with the extracellular pH. Pyrimidinone 8 can inhibit hDMT1-mediated iron uptake, with an IC50 of 13.8 μM.
  • HY-126301
    DMT1 blocker 1
    		Inhibitor 99.79%
    DMT1 blocker 1 (compound 6f) is a blocker of divalent metal transporter 1 (DMT1) with an IC50 of 0.64 μM, is expected to block iron uptake by enterocytes in vivo.
  • HY-107980
    DS28120313
    		Inhibitor 98.00%
    DS28120313 (compound 32) is an orally hepcidin production inhibitor with an IC50 of 0.093 μM.
  • HY-P990618
    LY2928057
    		Inhibitor
    LY2928057 is a CHO-expressed human antibody that targets SLC40A1/Ferroportin. The predicted molecular weight (MW) of LY2928057 is 150 kDa. The isotype control for LY2928057 can be referenced as Human IgG4 kappa, Isotype Control (HY-P99003).
  • HY-P990429
    Anti-Hepcidin/HAMP Antibody
    		Inhibitor
    Anti-Hepcidin/HAMP Antibody is a CHO-expressed human antibody that targets Hepcidin/HAMP. Anti-Hepcidin/HAMP Antibody has huIgG1 heavy chain and huλ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for Anti-Hepcidin/HAMP Antibody can refer to Human IgG1 kappa, Isotype Control (HY-P99001).