2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Glutathione Reductase
  5. Glutathione Reductase Inhibitor

Glutathione Reductase Inhibitor

Glutathione Reductase Inhibitors (2):

Cat. No. Product Name Effect Purity
  • HY-12542S
    Dantrolene-13C3
    		Inhibitor ≥99.0%
    Dantrolene-13C3 is the 13C3 labeled Dantrolene. Dantrolene (F368), a muscle relaxant, non-competitively inhibits human erythrocyte glutathione reductase. Ki and IC50 values are 111.6 μM and 52.3 μM, respectively. Dantrolene is a ryanodine receptor antagonist and Ca2+ signaling stabilizer. Dantrolene can be used for the research of muscle spasticity, malignant hyperthermia, Huntington's disease and other neuroleptic malignant syndrome.
  • HY-126849
    3-Morpholinosydnonimine
    		Inhibitor
    3-Morpholinosydnonimine (SIN-1) is a spontaneous ROS/RNS generator and peroxynitrite donor. 3-Morpholinosydnonimine induces oxidative stress-induced chondrocyte apoptosis and necrosis. 3-Morpholinosydnonimine inhibits the migration, proliferation and neointima formation of vascular smooth muscle cells by inhibiting the expression of annexin A2. In addition, low doses of 3-Morpholinosydnonimine shows protective effects on Zn2+ treated nerve cells.